Am wondering if murder, planning to murder, and domestic violence are brain disorders…
If so, or even probably so, this is a real wake up call for prison reform…
From the 23 April 2013 item at the National Institute of Mental Health
A rethink is needed in terms of how we view mental illness, stated National Institute of Mental Health Director Thomas Insel, M.D., in a recent TEDx talkat the California Institute of Technology (Caltech) in Pasadena.
Deaths from medical causes such as leukemia and heart disease have decreased over the past 30 years. The same cannot be said of the suicide rate, which has remained the same. A vast majority of suicides—90 percent—are related to mental illnesses such as depression and schizophrenia.
Insel believes part of the problem is that mental illness is referred to either as a mental or behavioral disorder. “We need to think of these as brain disorders,” he said, adding that for these brain disorders, behavior is the last thing to change.
Insel walked the audience through recent advances in neuroscience, including the Human Connectome, which indicates that mental illness may be more of a neuronal connection or circuit disorder. The earlier these circuits are identified, he said, the earlier preventive treatments could be used to save the lives of people with mental illnesses.
“If we waited for the ‘heart attack,’ we would be sacrificing 1.1 million lives every year in this country,” he said. “That is precisely what we do today when we decide that everyone with one of these brain disorders, brain circuit disorders, has a behavior disorder. We wait until the behavior emerges. That’s not early detection, that’s not early prevention.”
- Toward A New Understanding of Mental Illness (thesecretkeeper.net)
- A Break From Politics: Toward a new understanding of mental illness (freakoutnation.com)
- Once, people suffering from a mental illness were hidden … (jillsmentalhealthresources.wordpress.com)
- What Does It Really Mean for Me to Have a Mental Illness? (thedancingwriterblog.wordpress.com)
- Vaughan Bell: news from the borders of mental illness (guardian.co.uk)
- Mental Health Awareness Month (irishdragon7.wordpress.com)
- Medical Brain Disorders~The Benefits of Exercise (keepchoosingconsistency.com)
Please read the entire article, there are many factors that need to be “teased out” in future studies (as the author emphasizes).
A fascinating read, nonetheless.
It’s a common lament among parents: Kids are growing up too fast these days. Parents worry about their kids getting involved in all kinds of risky behavior, but they worry especially about their kids’ forays into sexual relationships. And research suggests that there may be cause for concern, as timing of sexual development can have significant immediate consequences for adolescents’ physical and mental health.
But what about long-term outcomes? How might early sexual initiation affect romantic relationships in adulthood?
Psychological scientist Paige Harden of the University of Texas at Austin wanted to investigate whether the timing of sexual initiation in adolescence might predict romantic outcomes — such as whether people get married or live with their partners, how many romantic partners they’ve had, and whether they’re satisfied with their relationship — later in adulthood…
- Young Porn Users Need Longer To Recover Their Mojo (psychologytoday.com)
- Fathers Matter When It Comes To Their Teenager’s Sexual Behavior (medicalnewstoday.com)
- Ontario slammed for outdated sex ed and mental health curriculum (metronews.ca)
- Does Your Child Have a Mental Health Disorder? (psychologytoday.com)
From the 19 July article at Digitial Medicine
Consumer mHealth is here. There has been a spurt of entrepreneurship in this field and some Indian phone/ mobile based start-ups have been launched over the past couple of years. Mainly, they have been services meant to connect healthcare consumers with doctors via phone (like Ask a Doctor from Vodafone, Mediphone by Religare technologies, Dial UR Doctor and Mera Doctor). Most of these tools are voice based and sometimes don’t even fit the rigid definitions of mHealth. Further, they are all healthcare professional specific and have pointedly ignored patients in any decision making process.
Not that all mHealth projects in India are in the private sector. The government of India has also been active in harnessing the reach of mobile phones in the country with some projects in Public health like in ensuring treatment compliance in DOTS Program and in healthcare reporting at grass roots level. …
..The latest mHealth project by the government of India looks to strike at the alleged root of costly medical care : the widely variable costs of branded drugs. The Indian government has taken the initiative to use simple messaging services (SMS) to educate the public on drug prices.
Here is how it works: Once the person sends a text message of the prescribed brand of drug to a particular number from his mobile, he will receive two to three options of the same medicine, along with the price differential. Say, a patient is prescribed a popular anti-infective like Augmentin (GlaxoSmithKline). He types in Augmentin and sends the SMS to the designated number. He would get a return SMS, possibly mentioning Moxikind CV (Mankind), which is substantially cheaper. But sources said that all responses would come with a caution: please consult the doctor before popping the alternative (pill).
- How mobile phones have changed Africa (cnn.com)
- Seven ways mobile phones have changed lives in Africa (textually.org)
- Revolutionising Medical Care With Mobiles (epiphanysearch.co.uk)
- The Investor’s View of Pharma’s Plunge Into Mobile Apps (medmeme.com)
This morning I stumbled upon LiveScience.com while perusing January’s Internet Reviews at College and Research Library News.
Live Science provide news in the areas of science, health, and technology for a general academic audience, especially undergraduates.It is a commercial site that is part of the TechMedia Network (which also includes TechNews Daily and Business News Daily). LiveScience content is often featured at partner sites including Yahoo and MSNBC.com. Most of the professional journalists on the editorial staff hold advanced degrees in technology or the sciences.
The site can be a big overwhelming at first with its images and video links, but there is wealth of information for the patient!
The features include:
- 11 subject areas in the bar at the top of the page – “Space,” “Animals,” “Health,” “Environment,” “Technology,” “History,” “Culture,” “Video,” Strange News,” “Images,” and “Topics.”
- “Top Stories” section typically presents five current news items along with a variety of rotating images.
- Images (containing considerable archives) with links to albums, infographics, and wallpapers
From the 6 January 2012 US Food and Drug Administration (FDA)
Stem cell therapies offer the potential to treat diseases or conditions for which few treatments exist.
Stem cells, sometimes called the body’s “master cells,” are the precursor cells that develop into blood, brain, bones and all of your organs. Their promise in medical treatments is that they have the potential to repair, restore, replace and regenerate cells that could then be used to treat many medical conditions and diseases.
But the Food and Drug Administration (FDA) is concerned that the hope that patients have for cures not yet available may leave them vulnerable to unscrupulous providers of stem cell treatments that are illegal and potentially harmful.
FDA cautions consumers to make sure that any stem cell treatment they are considering has been approved by FDA or is being studied under a clinical investigation that has been submitted to and allowed to proceed by FDA.
FDA has approved only one stem cell product [Flahiff's emphasis], Hemacord, a cord blood-derived product manufactured by the New York Blood Center and used for specified indications in patients with disorders affecting the body’s blood-forming system.
Regulation of Stem Cells
FDA regulates stem cells in the U.S. to ensure that they are safe and effective for their intended use.
“Stem cells can come from many different sources and under the right conditions can give rise to many different cell types,” says Stephanie Simek, Ph.D., deputy director of FDA’s Office of Cellular, Tissue and Gene Therapies.
Stem cells that come from bone marrow or blood are routinely used in transplant procedures to treat patients with cancer and other disorders of the blood and immune system.
Umbilical cord blood is collected from a placenta with the birth mother’s consent. Cord blood cells are then isolated, processed, and frozen and stored in a cord blood bank for future use. Cord blood is regulated by FDA and cord blood banks must follow regulatory requirements.
But there are many other stem cell products, including other cord blood-derived products, that have been reviewed by FDA for use in investigational studies, says Simek. Investigational products undergo a thorough review process as the sponsor prepares to study the safety and effectiveness of the product in adequate and well-controlled human studies (clinical trials).
As part of this review, the sponsor must show how the product will be manufactured so that FDA can make certain that appropriate steps are being taken to help assure the product’s safety, purity and potency. FDA also requires that there be sufficient data generated from animal studies to aid in evaluating any potential risks associated with the use of these products.
Consumers need to be aware that at present–other than cord blood for certain specified indications–there are no approved stem cell products.
Advice for Consumers
- If you are considering stem cell treatment in the U.S., ask your physician if the necessary FDA approval has been obtained or if you will be part of an FDA-regulated clinical study. This also applies if the stem cells are your own. Even if the cells are yours, there are safety risks, including risks introduced when the cells are manipulated after removal.There is a potential safety risk when you put cells in an area where they are not performing the same biological function as they were when in their original location in the body,” says Simek. Cells in a different environment may multiply, form tumors, or may leave the site you put them in and migrate somewhere else.
- If you are considering having stem cell treatment in another country, learn all you can about regulations covering the products in that country. Exercise caution before undergoing treatment with a stem cell-based product in a country that—unlike the U.S.—may not require clinical studies designed to demonstrate that the product is safe and effective. FDA does not regulate stem cell treatments used in solely in countries other than the United States and typically has little information about foreign establishments or their stem cell products.
Thwarting a Stem Cell Scheme
In December, 2011, three men were arrested in the United States and charged with 15 counts of criminal activity related to manufacturing, selling and using stem cells without FDA sanction or approval.
According to the criminal indictment, one of the accused, a licensed midwife who operated a maternity care clinic in Texas, obtained umbilical cord blood from birth mothers, telling them it was for “research” purposes. Instead, the midwife sold the cord blood to a laboratory in Arizona which, in turn, sent the blood to a paid consultant at a university in South Carolina. The owner of the laboratory in Arizona was convicted in August 2011 of unlawfully introducing stem cells into interstate commerce. She faces up to 3 years in prison and a fine of up to $10,000.
The consultant, an assistant professor, used university facilities to manufacture stem cell products. He then sent the products back to the lab, which sold them to a man representing himself as a physician licensed in the U.S. The man then traveled to Mexico to perform unapproved stem cell procedures on people suffering from cancer, multiple sclerosis and other autoimmune diseases.
The three defendants allegedly received more than $1.5 million from patients seeking treatment for incurable diseases.
“Scammers like these offer false hope to people with incurable diseases in order to line their own pockets with money,” says Special Agent in Charge Patrick J. Holland of FDA’s Office of Criminal Investigations (OCI), Kansas City Field Office. “FDA will continue to aggressively pursue perpetrators who expose the American public to the dangers of unapproved stem cells and ensure that they are punished to the full extent of the law.”
FDA’s OCI worked the case with the Federal Bureau of Investigations and the Internal Revenue Service’s Criminal Investigations Division.
This article appears on FDA’s Consumer Updates page, which features the latest on all FDA-regulated products.
- Stem Cells (Medline Plus) has links to overviews, news items, specific conditions, research (including clinical trials and research news from reputable organizations), directories and organizations
- Stem Cell Information(US National Institutes for Health) includes links to
- FDA Warns About Stem Cell Claims – Information You Should Know (regcompliance.wordpress.com)
- Stem Cells: Worldwide Markets for Transplantation, Cord Blood Banking and Drug Development (prnewswire.com)
- American scientist arrested in stem-cell clinic sting (blogs.nature.com)
- FBI crackdown on unproven stem cell therapies (newscientist.com)
- FBI crackdown on unproven stem cell therapies (newscientist.com)
- 3 Arrested for Peddling Miracle Stem Cell Cure (foxnews.com)
- Stem Cell Fraud: A 60 Minutes investigation (cbsnews.com)
- Legislator says stem cells helped ” Times Record News (wingright.org)
- Flexible Adult Stem Cells, Right There In Your Eye (medicalnewstoday.com)
- What Is Autologous Stem Cell Transplantation? (everydayhealth.com)
- Video: Preview: Stem Cell Fraud (cbsnews.com)
- FDA Approves Cord Blood For Stem Cell Transplant (medicalnewstoday.com)
- The FDA, Politics and Journalistic Fraud: The Stem Cell Battle in America (erasetheneed.wordpress.com)
- Texas prepares to fight for stem cells (nature.com)
Evidence on cost savings and health benefits of nutritional intervention published in the Journal of the Academy of Nutrition and Dietetics
Philadelphia, PA — The Academy of Nutrition and Dietetics has prepared a request to submit to the Centers for Medicare and Medicaid Services (CMS) to expand coverage of medical nutrition therapy (MNT) for specific diseases, including hypertension, obesity, and cancer, as part of the CMS National Coverage Determination (NCD) Process. Most chronic health conditions can be controlled or treated with medical nutrition therapy, yet Medicare will only reimburse nutrition therapy services provided by a registered dietitian for individuals with diabetes and renal disease. “That’s just not enough if we want to improve the health of the nation and rein in escalating healthcare costs,” says Marsha Schofield, MS, RD, LD, the Academy’s Director of Nutrition Services Coverage.
The article is “The Academy of Nutrition and Dietetics National Coverage Determination Formal Request [Full Text of the article],” by Prashanthi Rao Raman, Esq, MPH, and Erica Gradwell, MS, RD, in the Journal of the Academy of Nutrition and Dietetics, Volume 112, Issue 1 (January 2012) published by Elsevier.
In an accompanying podcast Ms. Schofield, Ms. Blankenship, and Ms. Gradwell discuss the NCD process undertaken by the Academy and share insights about its potential impact on healthcare and the role of the registered dietitian. The podcast is available at http://andjrnl.org/content/podcast.
- The Academy of Nutrition and Dietetics advocates for expanded nutritional coverage under Medicare (medicalxpress.com)
- The Academy of Nutrition and Dietetics advocates for expanded nutritional coverage under Medicare (eurekalert.org)
- A Dietitian Reflects on the Recent Nutrition Conference (fooducate.com)
- The ADA Needs to Change More than just its Name (fooducate.com)
- Medicare Offers Medical Nutrition Therapy (mayorshealthline.wordpress.com)
Researchers have developed a bandage that stimulates and directs blood vessel growth on the surface of a wound. The bandage, called a “microvascular stamp,” contains living cells that deliver growth factors to damaged tissues in a defined pattern. After a week, the pattern of the stamp “is written in blood vessels,” the researchers report.
A paper describing the new approach will appear as the January 2012 cover article of the journal Advanced Materials.
“Any kind of tissue you want to rebuild, including bone, muscle or skin, is highly vascularized,” said University of Illinois chemical and biomolecular engineering professor Hyunjoon Kong, a co-principal investigator on the study with electrical and computer engineering professor Rashid Bashir. “But one of the big challenges in recreating vascular networks is how we can control the growth and spacing of new blood vessels.”
“The ability to pattern functional blood vessels at this scale in living tissue has not been demonstrated before,” Bashir said. “We can now write features in blood vessels.”
Other laboratories have embedded growth factors in materials applied to wounds in an effort to direct blood vessel growth. The new approach is the first to incorporate live cells in a stamp. These cells release growth factors in a more sustained, targeted manner than other methods, Kong said. …
- Team designs a bandage that spurs, guides blood vessel growth (eurekalert.org)
- Team designs a bandage that spurs, guides blood vessel growth (physorg.com)
- Hydrogel helps grow new scar-free skin over third degree burns (gizmag.com)
Whether you call it Health 2.0, Medicine 2.0, or e-Health 2.0, the Internet is changing medicine in ways that challenge the status quo. This article explores how a group of amateurs who call themselves “health hackers” and “citizen scientists” are trying to use the Internet to connect with other patients, run experiments, and conduct clinical trials on their own diseases.
Dr. Gunther Eysenbach states “Medicine 2.0 applications, services and tools are Web-based services for health care consumers, caregivers, patients, health professionals, and biomedical researchers, that use Web 2.0 technologies as well as semantic web and virtual reality tools, to enable and facilitate specifically social networking, participation, apomediation, collaboration, and openness within and between these user groups.” One review examined 46 different definitions of Health 2.0, and Eysenbach’s definition does not emphasize a key component of the concept: amateurs can use these new Internet tools to do work that in the past was only done by professionals….
Charles Blanke, MD, Director of Gastrointestinal Oncology at the Oregon Cancer Institute summarizes the advantages and disadvantages of their patient-initiated approach:
This is powerful and compelling work! I remain incredibly impressed by the data-coordinating abilities of the Life Raft personnel. I see the major purpose of this sort of data as hypothesis generating. Unfortunately, it cannot be free of bias and thus cannot stand by itself, but it certainly can point investigators and the Company in the right direction and let us know what we need to be looking at more closely. Thus, its importance cannot be overstated….
,,,The tension between the traditional approach to medical research and patient-initiated research can only be resolved by cooperation and two-way communication between the two groups. The Mayo Clinic and PXE examples clearly show that both groups can benefit by meaningful and respectful partnership. The AIDS and ALS examples demonstrate that patients with few options and new Internet tools will continue to push the traditional research community to be open to new ideas, new approaches, and new possibilities. Gilles Frydman, founder of the Association of Cancer Online Resources, has stated, “Better-informed people are more willing to participate in the advancement of science. Those patients taking Gleevec do not consider themselves guinea pigs. They are recipients of experimental medicine.”…
- DocGreet Steadily Grows as the Leader in Health 2.0 and Medical Social Media (prweb.com)
- Connect with Project HealthDesign at Health 2.0 (projecthealthdesign.typepad.com)
- Reflections on the Medicine 2.0 conference at Stanford #med2 (medicineandtechnology.com)
- Health IT and Patient Safety: Building Safer Systems for Better Care (jflahiff.wordpress.com)
- During the Fifth Annual Health 2.0 Conference, Dr. James Mault of HealthyCircles will Showcase Innovative Technology that will Help Transform Health Care (prweb.com)