Link Between Anxiety Disorders And Cellular Metabolism
From the 16 May 2012 article at Medical News Today
Anxiety disorders, ranging from social phobia to post-traumatic stress disorder, are the most common psychiatric diseases in the United States. Research in mice suggests a link between the gene that encodes Glyoxylase 1 (GLO1) and increased anxiety; however, the mechanism underlying this association has remained unclear.
The normal role of GLO1 is to degrade cytotoxic byproducts of glycolysis, a function which has no obvious connection to anxiety.
Margaret Distler and colleagues at the University of Chicago asked whether the primary substrate of GLO1, methylglyoxal, might have undocumented neurological effects. Using a mouse model, they demonstrated that methylglyoxal stimulates robust activity from GABAA receptors, which are neuron receptors that respond to neurotransmitters. …
Related articles
- Cellular metabolism linked to anxiety disorders (eurekalert.org)
- Mystery gene reveals new mechanism for anxiety disorders (eurekalert.org)
- Mystery gene reveals new mechanism for anxiety disorders (sciencedaily.com)
About
This blog presents a sampling of health and medical news and resources for all. Selected articles and resources will hopefully be of general interest but will also encourage further reading through posted references and other links. Currently I am focusing on public health, basic and applied research and very broadly on disease and healthy lifestyle topics.
Several times a month I will post items on international and global health issues. My Peace Corps Liberia experience (1980-81) has formed me as a global citizen in many ways and has challenged me to think of health and other topics in a more holistic manner. (For those wishing to see pictures of a 2009 Friends of Liberia service trip to this West African country, please visit www.fol.org. My photo album is included).
Do you have an informational question in the health/medical area?
Email me at jmflahiff@yahoo.com
I will reply within 48 hours.
This blog is a companion site to my Health and Medical News and Resources Web site with…
- Informational sites and guides
- Links to help from others (as health care providers and support groups)
- Interactive tools (as health calculators and apps)
- Select related news sites and blogs
My professional work experience and education includes over 10 years experience as a medical librarian and a Master’s in Library Science. In my most recent position I enjoyed contributing to our library’s blog, performing in depth literature searches, and collaborating with faculty, staff, students, and the general public.
While I will never be be able to keep up with the universe of current health/medical news,
I subscribe to the following to glean entries for this blog
- Medical News Today, a MediLexicon International daily online health news product
- MedLib-L ,a medical librarian discussion list
- Science Daily – Your source for the latest research news
- A Consumer and Patient Health (CAPHIS) discussion list , by a section of the Medical Library Association (MLA)
- MedlinePlus email updates from the US National Institutes of Health
- Public Health Partners from the National Library of Medicine
- US Agency for Healthcare Research and Quality (AHRQ) electronic newsletter with updates on the agency’s efforts to “improve the quality, safety, efficiency, and effectiveness of health care for all Americans”
- Krafty (Medical)Librarian,” a collection of writings from Michelle Kraft on items of interest to medical librarians. She tends to write on technology and medical libraries but she also writes about things in general on librarianship, medicine and health”
- Research Buzz, “news about search engines, digital archives, online museums, databases, and other Internet information collections since 1998″
- Library Journal – Breaking News
- librarian.net by librarian consultant Jessamyn West
- The Cornflower, the blog of the National Network of Libraries of Medicine Greater Midwest Region
- DocuTicker with “abstracts from ‘grey literature’: PDF reports published by government agencies, think tanks, NGOs, research institutes and other public interest groups”
- PubMed New and Noteworthy, updates from the largest indexer of biomedical journals in the world
- Free Government Information, a ”place for initiating dialogue and building consensus among the various players (libraries, government agencies, non-profit organizations, researchers, journalists, etc.) who have a stake in the preservation of and perpetual free access to government information”
- Scout Report, a “weekly publication offering a selection of new and newly discovered Internet resources of interest to researchers and educators”
- Latest from Brookings Institute, independent research reports on social and political issues
- KevinMD.com -”Social Media’s leading physician voice”
- EurekAlert-Medicine and Health
