Health and Medical News and Resources

General interest items edited by Janice Flahiff

[Press release] Sweat glands heal injuries

From the 4 February 2014 press release at EurkAlert

This news release is available in German.

 IMAGE: A biopsy punch arranges the biopolymer substrate into the appropriate shape (left). Cells then colonize these circular discs in cell culture vessels (right).

Click here for more information. 

It all began with the pancreas. Prof. Charli Kruse, head of the Fraunhofer Research Institution for Marine Biotechnology EMB in Lübeck, still remembers it well. The researchers had isolated some cells taken from the organ in a petri dish as part of their research – their aim was to investigate the function of the protein Vigilin, which is produced in the gland cells. “Suddenly we realized that these cells were reproducing in an unusual way, since the microscope showed not only gland cells in the dish but nerve and muscle cells, too.” Stem cells had formed out of the gland tissue and multiplied to form a variety of different cells. It quickly became apparent that other gland cells shared the same capability: “We slowly worked our way outward from the internal organs until we got to the skin – and the sweat glands. Again, this yielded the same result: a petri dish full of stem cells.” Up to now the sweat glands haven’t really received much attention since laboratory animals such as mice or rats have them only on their paws. A human being, on the other hand, possesses up to three million – predominantly on the soles of the feet, palms of the hand, armpits and forehead.

Healing stem cells obtained from the armpit

Biologists and medics use stem cells to obtain new tissue to replace cells that are damaged or diseased. They play a particularly important role in healing wounds. Stem cells taken from the patient’s own body are ideal because there is no chance of the body rejecting them. Getting at them, however, requires a cumbersome operation to extract the stem cells either from bone marrow or from the blood. “The sweat glands are significantly easier to get to. All that is required is a short walk-in walk-out visit to your dermatologist. We can obtain stem cells from less than 3 millimeters of underarm skin,” explains Kruse. When grafted to a skin injury, these stem cells can have a very beneficial effect on the healing process. Whether it is the cells themselves that build new skin cells and blood vessels or whether their role is to manage healing processes by releasing growth hormones that in turn activate immune cells is currently undergoing investigation.

Tests conducted by the scientists on animals and on human skin in the petri dish have demonstrated the beneficial effect of stem cells in healing injuries.

 

Read the entire press release here

Advertisements

February 5, 2014 - Posted by | Medical and Health Research News | , , , ,

No comments yet.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: