Health and Medical News and Resources

General interest items edited by Janice Flahiff

[Press release] Genetic changes in Ebola virus could impede potential treatments

Thinking of my Liberia FB friends. One I met (he is a nurse) in 2009 while doing service projects in Liberia. He is a dean of a college near the capital (Monrovia)…while school is out, he is working with Doctors Without Borders in Monrovia.
Another is a former student of mine (1980/81…when I was a Peace Corps volunteer. He is now a Methodist deacon, in Ganta, the second largest city in Liberia. Ganta is 10 miles up the road from where I volunteered. Back in 2009, he recognized me in front of the church in Ganta, where we did some volunteer projects!
Third person is a health screener in Kpain, where I was a Peace Corps volunteer. He put in a FB friend request. He is from Nigeria.
These three men are among my heroes. They are doing so much with so little. Reaffirmed my belief that Liberians are resilient and creative.

USAMRIID Logo

USAMRIID Logo (Photo credit: Wikipedia)

Genetic changes in Ebola virus could impede potential treatments

 

Ebola Pathenogensis

Ebola Pathenogensis (Photo credit: Wikipedia

 

 

From the US Army Medical Research Institute of Infectious Diseases 20 January 2015 press release

 

Scientists studying the genetic makeup of the Ebola virus currently circulating in West Africa have identified several mutations that could have implications for developing effective drugs to fight the virus.

In today’s online edition of the journal mBio, senior author Gustavo F. Palacios, Ph.D., and colleagues describe the “genomic drift,” or natural evolution of the virus, and how it may interrupt the action of potential therapies designed to target the virus’s genetic sequence.

According to Palacios, who directs the Center for Genome Sciences at the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID), three types of genetic sequence-based treatments are being evaluated during the current outbreak: monoclonal antibody, small-interfering RNA (siRNA), and phosphorodiamidate morpholino oligomer (PMO) drugs. All were developed using Ebola virus strains from two smaller outbreaks that occurred in 1976 and 1995.

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January 23, 2015 - Posted by | Medical and Health Research News | , , , ,

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