[Special Nature/Scientific American 2014 issue] Cancer: The March on Malignancy

 

This 2014 issue of Nature (in collaboration with Scientific American)  is free to read by all.

Contents include

• Therapy
  

  This Time it’s Personal

  Tailoring cancer treatment to individual and evolving tumours is the way of the future, but scientists are still hashing out the details

• Nanotechnology
  

  Deliver on a Promise

  Effective treatment of cancer requires getting the drugs precisely to the target. Enter the nanoparticle

• Comparative Biology
  

  Naked Ambition

  A subterranean species that seems to be cancer-proof is providing promising clues on how we might prevent the disease in humans

• Developing World
  

  Global Warning

  Much of the world is ill-equipped to cope with its rising cancer burden and are pushing prevention and screening

• Prevention
  

  Air of Danger

  Carcinogens are all around us, so scientists are broadening their ideas of environmental risk

Statistics

Attacking an Epidemic

Despite a huge amount of funding and research, regional and individual differences in cancer trends make it a hard disease to wipe out

Clinical Trials

More Trials, Fewer Tribulations

Grouping patients according to their molecular profile can make for better and faster drug approval decisions

Bioinformatics

Big Data Versus the Big C

The torrents of data flowing out of cancer research and treatment are yielding fresh insight into the disease

Perspective

Learning to Share

Genomics can provide powerful tools against cancer — but only once clinical information can be made broadly available

Biology

Three Known Unknowns

Even as cancer therapies improve, basic questions about drug resistance, tumour spread and the role of normal tissue remain unanswered