Health and Medical News and Resources

General interest items edited by Janice Flahiff

Looking for Biological Product Information? Try the FDA’s Purple Book

From the February 20 article at Regulatory Focus News

“Regulatory Focus: FDA Launches Searchable Purple Book. “The US Food and Drug Administration (FDA) on Monday unveiled the first version of its searchable online database of biological product** information, known as the Purple Book. Building off the previous PDF lists of biological products, the database now allows for easier searches and includes information on product names (proprietary and proper), the type of biologics license application (BLA) that was submitted, strength of the biologic, dosage form, product presentation, license status, BLA number and approval date.” I didn’t know how a “biological product” was defined. I got educated via this FDA PDF.


Click Image for Larger Version

***What is a biological product?

Biological products include a wide range of products such as vaccines, blood and blood components, allergenics, somatic cells, gene therapy, tissues, and recombinant therapeutic proteins. Biologics can be composed of sugars, proteins, or nucleic acids or complex combinations of these substances, or may be living entities such as cells and tissues. Biologics are isolated from a variety of natural sources – human, animal, or microorganism – and may be produced by biotechnology methods and other cutting-edge technologies. Gene-based and cellular biologics, for example, often are at the forefront of biomedical research, and may be used to treat a variety of medical conditions for which no other treatments are available.

August 17, 2020 Posted by | Finding Aids/Directories | , , , , , , , | Leave a comment

Yoga Shown to Improve Anxiety, Study Finds

From the August 12, 2020 NYU Langone Health NewsHub

“Yoga improves symptoms of generalized anxiety disorder, a condition with chronic nervousness and worry, suggesting the popular practice may be helpful in treating anxiety in some people.

Led by researchers at NYU Grossman School of Medicine, a new study found that yoga was significantly more effective for generalized anxiety disorder than standard education on stress management, but not as effective as cognitive behavioral therapy (CBT), the gold standard form of structured talk therapy that helps patients identify negative thinking for better responses to challenges.”

Read the entire article here.

August 17, 2020 Posted by | Consumer Health, Psychology | , , , | Leave a comment

Aging memories may not be ‘worse,’ just ‘different’

From The August 20, 2020 news release of the Washington University in St. Louis

Excerpts
“Memory is the first thing to go.”

Everyone has heard it, and decades of research studies seem to confirm it: While it may not always be the first sign of aging, some faculties, including memory, do get worse as people age.

It may not be that straightforward…..

….Much of the activity he was interested in is in an area of the brain referred to as the posterior medial network — which includes regions in the midline and toward the backside of the brain. In addition to memory, these areas are heavily involved in representing context and situational awareness. Some of those areas showed decreased activity in the older adults.

We do think the differences are memory-related,” Reagh said. At the boundaries, they saw differences in the levels of activity in the hippocampus that was related to memory in a different measurement — “story memory,” he called it.

“There might be a broad sense in which the hippocampus’s response to event boundaries predicts how well you are able to parse and remember stories and complex narratives,” no matter one’s age, Reagh said.

But for older adults, closer to the front of the brain, particularly the medial prefrontal cortex, things were looking up.

Activity in that area of the brain was ramped up in older adults. This area is implicated in broad, schematic knowledge — what it’s like to go to grocery store as opposed to a particular grocery store.

“What might be happening is as older adults lose some responsiveness in posterior parts of the brain, they may be shifting away from the more detailed contextual information,” Reagh said. But as activity levels heighten in the anterior portions, “things might become more schematic. More ‘gist-like.’”

In practice, this might mean that a 20-year-old noting an event boundary in a movie might be more focused on the specifics — what specific room are the characters in? What is the exact content of the conversation? An older viewer might be paying more attention to the broader picture — What kind of room are the characters in? Have the characters transitioned from a formal dinner setting to a more relaxed, after-dinner location? Did a loud, tense conversation resolve into a friendly one?

“Older adults might be representing events in different ways, and transitions might be picked up differently than, say, a 20-year-old,” Reagh said.

“An interesting conclusion one could draw is maybe healthy older adults aren’t ‘missing the picture.’ It’s not that the info isn’t getting in, it’s just it’s getting in differently.”

August 17, 2020 Posted by | biology | , , , | Leave a comment

New study documents increasing frequency, cost, and severity of gunshot wounds that require surgical intervention

From the August 10 2020 news release from the American College of Surgeons

Researchers hope findings drive changes to address violence and hospital costs

“The rise in firearm violence has coincided with an increase in the severity of injuries firearms inflict as well as the cost of operations to treat those injuries; policy makers must be more aggressive in addressing violence to curb these trends, researchers report in a large national study of gunshot wounds that appears as an “article in press” on the Journal of the American College of Surgeons website ahead of print.

“Taken together, our findings suggest that gun violence has increased in numbers, at least for the sector that meets surgical criteria, and that these injuries result in a substantial financial burden in addition to the obvious psychosocial burden and other downstream effects..

August 17, 2020 Posted by | Medical and Health Research News, statistics | , | Leave a comment

   

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