[News release] How we make emotional decisions

From the 28 May 2015 MIT news item

Neuroscientists identify a brain circuit that controls decisions that induce high anxiety.

Some decisions arouse far more anxiety than others. Among the most anxiety-provoking are those that involve options with both positive and negative elements, such choosing to take a higher-paying job in a city far from family and friends, versus choosing to stay put with less pay.

MIT researchers have now identified a neural circuit that appears to underlie decision-making in this type of situation, which is known as approach-avoidance conflict. The findings could help researchers to discover new ways to treat psychiatric disorders that feature impaired decision-making, such as depression, schizophrenia, and borderline personality disorder.

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The new study grew out of an effort to figure out the role of striosomes — clusters of cells distributed through the the striatum, a large brain region involved in coordinating movement and emotion and implicated in some human disorders. Graybiel discovered striosomes many years ago, but their function had remained mysterious, in part because they are so small and deep within the brain that it is difficult to image them with functional magnetic resonance imaging (fMRI).

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[Press release] What makes some women able to resist or recover psychologically from assault-related trauma?

Regions of the brain affected by PTSD and stress. (Photo credit: Wikipedia)

 

From the 2 March 2015 press release

In a study of 159 women who had been exposed to at least one assault-related potentially traumatic event, 30% developed major depressive disorder, which may be attributed to self-blame common to survivors of assault. Fewer women (21%) developed chronic posttraumatic stress disorder.

Mastery–the degree to which an individual perceives control and influence over life circumstances–and social support were most prevalent in women who did not develop a trauma-related psychiatric disorder after assault exposure, while mastery and posttraumatic growth were related to psychiatric recovery. These factors were less established in women with a current psychiatric disorder.

The Brain and Behavior findings have significance for the health and wellbeing of women, and for identifying individuals who are most in need of resilience-promoting interventions. “Women exposed to assault may present with post-trauma depression in lieu of posttraumatic stress disorder. Resilience factors like mastery and social support may attenuate the deleterious effects of an assault,” said lead author Heather L. Rusch. “The next step is to determine the extent that these factors may be fostered through clinical intervention.”

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