[Press release] NIH to partner with biopharmaceutical companies and nonprofits to diagnose/treat diseases

From the 5 February 2014 (US) National Institutes of Health press release

The Accelerating Medicines Partnership (AMP) is a bold new venture between the NIH, 10 biopharmaceutical companies and several non-profit organizations to transform the current model for developing new diagnostics and treatments by jointly identifying and validating promising biological targets of disease. The ultimate goal is to increase the number of new diagnostics and therapies for patients and reduce the time and cost of developing them.

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[At the risk of breaking copyright, this came via Twitter]

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AMP will begin with three to five year pilot projects in three disease areas:

• Alzheimer’s disease
• type 2 diabetes
• autoimmune disorders of rheumatoid arthritis and systemic lupus erythematosus (lupus)

For each pilot, scientists from NIH and industry have developed research plans aimed at characterizing effective molecular indicators of disease called biomarkers and distinguishing biological targets most likely to respond to new therapies.

Through this cross-sector partnership, which will be managed through the Foundation for the NIH (FNIH), NIH and industry partners are sharing expertise and resources — $230 million — in an integrated governance structure that enables the best informed contributions to science from all participants. A critical component of the partnership is that industry partners have agreed to make the AMP data and analyses publicly accessible to the broad biomedical community. These pilot projects will set the stage for broadening AMP to other diseases and conditions.

AMP Partners

Government	Industry	Non-Profit Organizations
FDANIH	AbbVieBiogen Idec Bristol-Myers Squibb GlaxoSmithKline Johnson & Johnson Lilly Merck Pfizer Sanofi Takeda	Alzheimer’s AssociationAmerican Diabetes Association Lupus Foundation of America Foundation for the NIH Geoffrey Beene Foundation PhRMA Rheumatology Research Foundation USAgainstAlzheimer’s

Budget: 5 years [$230 Million (Rounded) Total Project Funding]

($Millions)	Total Project	Total NIH	Total Industry
Alzheimer’s Disease	129.5	67.6	61.9
Type 2 Diabetes	58.4	30.4	28
Rheumatoid Arthritis and Lupus	41.6	20.9	20.7
Total	229.5	118.9	110.6

The Opportunity

The Challenge

The Impact

Governance

Related Information

• News: NIH, industry and non-profits join forces to speed validation of disease targets, February 4, 2014
• Director’s Blog: Introducing AMP: the Accelerating Medicines Partnership
• Multimedia
• Statement by the President