Safe Use of Complementary Health Products and Practices
Excerpt from NIH article, dated Sept 27, 2017
“As with any treatment, it is important to consider safety before using complementary health products and practices. Safety depends on the specific therapy, and each complementary product or practice should be considered on its own.”
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Two of the main safety concerns for dietary supplements are
- The possibilities of drug interactions—for example, research has shown that St. John’s wort interacts with drugs such as antidepressants in ways that can interfere with their intended effects
- The possibilities of product contamination—supplements have been found to contain hidden prescription drugs or other compounds, particularly in dietary supplements marketed for weight loss, sexual health including erectile dysfunction, and athletic performance or body-building.Two of the main safety concerns for dietary supplements are
- The possibilities of drug interactions—for example, research has shown that St. John’s wort interacts with drugs such as antidepressants in ways that can interfere with their intended effects
- The possibilities of product contamination—supplements have been found to contain hidden prescription drugs or other compounds, particularly in dietary supplements marketed for weight loss, sexual health including erectile dysfunction, and athletic performance or body-building.”
:
How Safe Is This Product or Practice?
Find safety information from a list of complementary health products and practices
Find FDA and FTC notices about recalls, tainted products, and other alerts and advisories
New Email Topic on ‘Know the Science’. Sign up & gain a better understanding of complex scientific topics.
From the US Center for Complementary and Integrative Health (a US government agency)
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Do You Have Questions About Integrative Health Approaches? [news release]
Here’s the contact us link –> https://nccih.nih.gov/health/clearinghouse?nav=govd
Time to Talk Tips on Complementary Health Practices [Reblog]
Time to Talk Tips on Complementary Health Practices Information Resources By Evelyn Cunico, M.A., M.S. Posted June 02, 2015 Background “Time to Talk Tips” is one of the resources in the…
Time to Talk Tips on Complementary Health Practices [reblog, resource]
From the 2 June 2015 post by Evelyn Cunico, M.A., M.S. at CHIMEconsumerhealth
“Time to Talk Tips” is one of the resources in the “Time to Talk Campaign,” managed by the National Center for Complementary and Integrative Health (NCCIH), at the National Institutes of Health (NIH).
Like any health-related decision, your decision about whether to use complementary health practices is central to your health and safety. Yet, information you find on the Web is not always specific to your illness or based on scientific evidence.
The NIH monthly consumer-friendly series, “Time to Talk Tips,” discusses specific health topics, together with the scientific evidence related to those topics. The series is designed to encourage you and your medical doctors or other healthcare providers to talk about any complementary practice that you are considering.
Examples of “Time to Talk Tips”
Each month, the series highlights a health topic. For example, topics include “Natural Products for the Flu and Colds,” and “What Consumers Need to Know about the Use of Dietary Supplements.”
The series includes simple tips, such as, taking vitamin C regularly does not reduce the likelihood of getting a cold, but may improve some cold symptoms, and some dietary supplements may interact with prescription or over-the-counter medications or other dietary supplements.
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[Press release] Complementary and alternative medicine for veterans and military personnel — update from Medical Care
From the 17 November 2014 press release
Special issue reports progress, but more work needed to incorporate CAM into military health settings
November 17, 2014 – A growing body of research evidence shows that complementary and alternative medicine (CAM) has health benefits for US military veterans and active duty personnel, according to a special December supplement to Medical Care. [All articles are free].The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
The special issue presents new studies and commentaries on the benefits and increasing use of CAM techniques in the Veterans Health Administration (VHA) and other military health settings. “The papers in this supplement represent promising steps to improve the health of veterans and active military personnel,” according to an introductory article by Guest Editors Stephanie L. Taylor, PhD, of Greater Los Angeles VA Healthcare System and A. Rani Elwy, PhD, of Edith Nourse Rogers Memorial Veterans Hospital, Bedford, Mass. “They mirror the countless stories we hear from veterans and their providers about the positive effect that CAM is having on their lives.”
Studies Show Value of CAM for Improving Health of Military Personnel
The supplement presents 14 original studies reporting on specific CAM therapies and on the current use, perceptions, and acceptance of CAM in veterans and current military personnel. The special issue of Medical Care is sponsored by the VHA’s Office of Patient Centered Care and Cultural Transformation.
Complementary and alternative medicine therapies are increasingly available, used, and appreciated by military patients, according to Drs Taylor and Elwy. They cite statistics showing that CAM programs are now offered at nearly 90 percent of VA medical facilities. Use CAM modalities by veterans and active military personnel is as at least as high as in the general population.
Previous systematic reviews have reported benefits of CAM treatments for many of the important problems seen in military populations, including chronic pain, anxiety, posttraumatic stress disorder (PTSD), and depression. Those prior results suggest that CAM therapies are “moderately effective” for these conditions–although these conclusions must be weighed against the weaknesses of the evidence base.
Highlights of the research included in the special issue include:
- Studies reporting benefits of specific types of meditation practices. One study finds that a mindfulness-based intervention reduced depression and improved psychological well-being in veterans with PTSD. A study of mindfulness-based stress reduction for veterans shows reductions in anxiety and depression, as well as suicidal thoughts.
- A report showing beneficial effects of acupuncture for veterans with PTSD. In addition to reduced severity of PTSD symptoms, the study shows improvements in depression, pain, and physical and mental health functioning. Another study finds that most veterans use vitamins and nutritional supplements, often substituting them for prescription drugs.
- Studies showing high rates of use and favorable perceptions found of CAM modalities among veterans of the Gulf War and Operation Enduring Freedom/Operation Iraqi Freedom. Veterans with PTSD are more likely to be accepting of CAM therapies.
- Reports describing the rates and preferred types of CAM mind-body and other modalities among military members and veterans, as well as on health care providers’ attitudes toward CAM. While VA providers vary in their knowledge of CAM, many perceive benefits for their patients.
A commentary by Laura P. Krejci, MSW, and colleagues of the VA’s Office of Patient Centered Care & Cultural Transformation discusses the role of CAM in meeting the “number one strategic priority” of providing “personalized, proactive, patient-driven health care to veterans.” Dr Wayne B. Jonas and colleagues of the Samueli Institute, Alexandria, Va., draw attention to several bodies of research on CAM in the US military. They conclude that current policy and priorities leave “the majority of active duty service members, veterans, and their families to fend for themselves, to pay for or go without the beneficial effects of CAM and integrative medicine practices.”
While the studies in the special issue show progress, Drs Taylor and Elwy stress the need for additional rigorous research to better understand CAM’s potential for managing important conditions seen in military populations. They conclude, “It is time for more funding to be awarded to CAM …to improve the capacity of the field to carry out rigorous CAM research, which in turn will benefit veterans and military personnel, as well as the general population.”
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[Press release] Discussing alternative medicine choices for better health outcomes

English: A graph of age-adjusted percent of adults who have used complementary and alternative medicine in 2002 in the United States according to the National Center for Complementary and Alternative Medicine. (Photo credit: Wikipedia)
From the 3 October 2014 press release at EurkAlert
Discussing alternative medicine choices for better health outcomes
In the field of medicine there has often been a divide between those who focus on modern medicine and those who prefer alternative practices. But pediatrician Sunita Vohra is a firm believer there should be room for both.
A new study from Vohra, a professor in the Faculty of Medicine & Dentistry’s Department of Pediatrics at the University of Alberta, and a pediatric physician for Clinical Pharmacology with Alberta Health Services, is giving insight into the use of alternative medicines by pediatric cardiac patients and how effective they are seen to be. “We wanted to know if the use of alternative therapies helped or not, and we wanted to know if it hurt them or not,” she says.
The study, published in the journal CMAJ Open, examined the use of alternative therapies such as multivitamins, minerals, chiropractic care and Aboriginal healing in 176 patients at the Stollery Children’s Hospital in Edmonton, Alberta, and the Children’s Hospital of Eastern Ontario (CHEO) in Ottawa, Ontario.
It found 64 per cent of patients at the Stollery Children’s Hospital reported using complementary and alternative medicine products and practices, compared with just 36 per cent at CHEO. Of those patients, Vohra says most had no regrets about their choices.
English: Classification of complementary and alternative therapies Italiano: Classificazione di terapie complementari e alternative (Photo credit: Wikipedia)
“The vast majority felt that they had been helped by the complementary therapy that they took and it was extremely unusual for them to report that they felt an adverse event had occurred because of it.”
The study also found one third of patients and their families did not discuss the use of alternative medicines with their physicians. Vohra believes it shows that patients may be reluctant to discuss their choices if they’re not sure how it will be received by health care providers.
That decision could have important health consequences, says Vohra, who also serves as director of the Complementary and Alternative Research and Education (CARE) program at the University of Alberta, and that patients’ discussing alternative therapies with health professionals is vital in order for them to make informed choices.
“There may be some therapies that help children feel better, but there may be others that, unbeknownst to the family, cause interaction between a specific natural health product and a prescription medicine. In that setting, instead of helping the child get better, harm may actually be happening.”
Vohra stresses the need for open communication and says children’s hospitals in Canada need to do a better job of providing information to patients looking at other avenues to health.
“That communication is essential because the health-care providers and the parents—together we are a team. And everyone’s hope is for that child’s better health.”
Other highlights from the study:
- Multi-vitamins were the most common complementary and alternative medicine products with 71 percent of patients using them, followed by vitamin C (22 per cent), calcium (13 per cent) and cold remedies (11.8 per cent)
- The most common practices include massage (37.5 per cent), faith healing (25 per cent), chiropractic (20 per cent), aromatherapy (15 per cent) and Aboriginal healing (7.5 per cent)
- Almost half (44 per cent) of patients used complementary and alternative medicine products along with conventional treatments. The study’s research was supported by funding from the Sick Kids Foundation and Alberta Innovates Health Solutions.
Related articles
Drugs From Nature, Then and Now – Medicines By Design
From the article at the US National Institutes of Health, last reviewed on October 27, 2011
Long before the first towns were built, before written language was invented, and even before plants were cultivated for food, the basic human desires to relieve pain and prolong life fueled the search for medicines. No one knows for sure what the earliest humans did to treat their ailments, but they probably sought cures in the plants, animals, and minerals around them.
[The table of contents]
He found that the ingredient, called parthenolide, appears to disable a key process that gets inflammation going. In the case of feverfew, a handful of controlled scientific studies in people have hinted that the herb, also known by its plant name “bachelor’s button,” is effective in combating migraine headaches, but further studies are needed to confirm these preliminary findings….
Related articles
Pain significantly reduced, quality of life improved by integrative medicine interventions

English: graph of age-adjusted percent of adults who have used complementary and alternative medicine: United States, 2002 (Photo credit: Wikipedia)
From the 24 July 2013 article at Medical News Today
An integrative approach to treating chronic pain significantly reduces pain severity while improving mood and quality of life, according to a new study from the Bravewell Practice-Based Research Network (BraveNet) published last month in BioMed Central Complementary and Alternative Medicine journal. Researchers found a reduction in pain severity of more than 20 percent and a drop in pain interference of nearly 30 percent in patients after 24 weeks of integrative care. Significant improvements in mood, stress, quality of life, fatigue, sleep and well-being were also observed.
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In keeping with the integrative medicine philosophy of individualized, patient-centered care, no standardized pre-specified clinical intervention for chronic pain was prescribed for all study participants. Instead, practitioners at each of the network sites devised integrative treatment plans for participating chronic pain patients. All BraveNet sites include integrative physicians, acupuncturists, mindfulness instructors, and yoga instructors; some also incorporate massage therapists, manual medicine therapists, fitness/movement specialists, dietician/nutritionists, psychologists, healing touch therapists, and other energy practitioners.
Related articles
- Integrative medicine interventions found to significantly reduce pain, improve quality of life (eurekalert.org)
- A New Model Of Understanding Chronic Pain & Depression May Offer Hope To Sufferers (medicalnewstoday.com)
- Accupuncture Found to Relieve Pain Better Than Traditional Treatments (liveinthenow.com)
- One Yoga Class Per Week Sufficient For Lower Back Pain Relief (asianscientist.com)
- Could chronic pain become a thing of the past? (express.co.uk)
- Yoga Helps Ease Lower Back Pain (medindia.net)
- Managing Horrible Pain with Narcotics (apluscaregiver.com)
Herbal medicine: 6 tips to consider when talking to your patients

Pictures of herb samples from categories of Chinese Herbs Substances for Topical Application (Photo credit: Wikipedia)
From the 4 July 2013 article at KevinMD.com
ROBIN FRIEDLANDER, MD | MEDS | JULY 4, 2013
Herbal medicines make most doctors cringe, laugh, or want to put blinders on and pretend they don’t exist. This is understandable. While allopathic medical education hammers pharmaceutical formulas and mechanisms of action into our brains, we learn little-to-nothing about herbs in medical school. Quite the opposite – we are most often told to uniformly discourage our patients from taking herbs out of concern for safety; a conversation stopper with little room for nuance.
In Western medicine, at best, herbs and plants are recognized for their role as an anchor ingredient in many pharmaceutical drugs. At worst, herbs are shunned for being unstudied and unregulated – fraught with reports of contamination, false-advertising and misuse by patients. This is thanks in large part to the Dietary Supplement Act of 1994, which allowed their sale without prescription.
Yet at least 15 million Americans say they take some form of herbal medication, and the dietary supplement market grosses $28 billion dollars annually. In other words, chances are that some of your patients are taking herbs, whether you know it or not.
First, some context: Not all herbs are restricted to mysterious Internet sites or eight hour energy drinks. Far from it. Tumeric root, a staple in Indian food, is a great example of an herbal medicine whose active ingredient, curcumin, has been proven to have anti-inflammatory, antioxidant, adaptogenic, and immunomodulatory properties. Not only has it been widely studied and used, but it also has basically no side-effects.
Ginger, cinnamon, not to mention others less likely to show up in your salad – milk thistle, for example – all have double-blind studies backing their claims. Indeed, many herbs can be a great sources of antioxidants, phytonutrients, and alkaloids, and have properties ranging from the anti-microbial to the anxiolytic. These anti-inflammatory properties can lend them a supportive role in the continuum of health and illness, helping nourish the body properly so it can do what it was designed to do – heal from and resist disease.
So how do you, as a Western doctor, with a responsibility to do no harm, approach herbs intelligently? The following is a pathway for addressing the use of herbal medicine in your practice even if you would never recommend an herb yourself.
1. Do your research. I find that the most easy-to-use and comprehensive guides are the online databases The Natural Standard, and The Natural Medicines Comprehensive Database, as well as the textbook, The Essential Guide to Herbal Safety. For a quick reference, the National Institutes of Health also offers the online“Herbs At A Glance,” patient-focused resource with information on the most common Western herbs. Finally, the American Journal of Cardiology published two helpful lists in 2010 summarizing common herb-drug interactions and herbs to avoid in patients with cardiovascular diseases. The databases and textbook in particular offer a digestible run-down of efficacy, contraindications, side effects, drug interactions, and pregnancy classification.
Related Resources
Related articles
- University of Ibadan to begin course on Herbal Medicine (whatsupibadan.com)

Logo of the United States National Center for Complementary and Alternative Medicine , part of the National Institutes of Health. (Photo credit: Wikipedia)
Cancer and Complementary Health Approaches
Introduction
People with cancer want to do everything they can to combat the disease, manage its symptoms, and cope with the side effects of treatment. Many turn to complementary health approaches, including natural products, such as herbs (botanicals) and other dietary supplements, and mind and body practices, such as acupuncture, massage, and yoga.
This fact sheet was produced through a collaboration between the National Center for Complementary and Alternative Medicine (NCCAM) and the National Cancer Institute (NCI). It provides an introductory overview of complementary health approaches that have been studied for cancer prevention, treatment of the disease, or symptom management, including what the science says about their effectiveness and any concerns that have been raised about their safety.
Key Facts
- Symptom management. A substantial amount of scientific evidence suggests that some complementary health approaches may help to manage some symptoms of cancer and side effects of treatment. For other complementary approaches, the evidence is more limited.
- Disease treatment. At present, there is no convincing evidence that any complementary health approach is effective in curing cancer or causing it to go into remission.
- Cancer prevention. A 2012 study indicated that taking a multivitamin/mineral supplement may slightly reduce the risk of cancer in older men. No other complementary health approach has been shown to be helpful in preventing cancer.
Keep in Mind
- Unproven products or practices should not be used to replace or delay conventional medical treatment for cancer.
- Some complementary approaches can interfere with standard cancer treatments or have special risks for people who have been diagnosed with cancer. Before using any complementary health approach, people who have been diagnosed with cancer should talk with their health care providers to make sure that all aspects of their care work together.
- Tell all your health care providers about any complementary health approaches you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care.
About Cancer
Cancer is a term for diseases in which abnormal cells divide without control. Cancer cells can invade nearby tissues and spread to other parts of the body through the bloodstream and the lymph system. Although cancer is the second leading cause of death in the United States, improvements in screening, detection, treatment, and care have increased the number of cancer survivors, and experts expect the number of survivors to continue to increase in the coming years. Detailed information on cancer is available from NCI at www.cancer.gov.
About Complementary Health Approaches
Complementary health approaches are a group of diverse medical and health care systems, practices, and products whose origins come from outside of mainstream medicine. They include such products and practices as herbal supplements, other dietary supplements, meditation, spinal manipulation, and acupuncture.
The same careful scientific evaluation that is used to assess conventional therapies should be used to evaluate complementary approaches. Some complementary approaches are beginning to find a place in cancer treatment—not as cures, but as additions to treatment plans that may help patients cope with disease symptoms and side effects of treatment and improve their quality of life.
Use of Complementary Health Approaches for Cancer
Many people who have been diagnosed with cancer use complementary health approaches.
- According to the 2007 National Health Interview Survey (NHIS), which included a comprehensive survey on the use of complementary health approaches by Americans, 65 percent of respondents who had ever been diagnosed with cancer had used complementary approaches, as compared to 53 percent of other respondents. Those who had been diagnosed with cancer were more likely than others to have used complementary approaches for general wellness, immune enhancement, and pain management.
- Other surveys have also found that use of complementary health approaches is common among people who have been diagnosed with cancer, although estimates of use vary widely. Some data indicate that the likelihood of using complementary approaches varies with the type of cancer and with factors such as sex, age, and ethnicity. The results of surveys from 18 countries show that use of complementary approaches by people who had been diagnosed with cancer was more common in North America than in Australia/New Zealand or Europe and that use had increased since the 1970s and especially since 2000.
- Surveys have also shown that many people with cancer do not tell their health care providers about their use of complementary health approaches. In the NHIS, survey respondents who had been diagnosed with cancer told their health care providers about 15 percent of their herb use and 23 percent of their total use of complementary approaches. In other studies, between 32 and 69 percent of cancer patients and survivors who used dietary supplements or other complementary approaches reported that they discussed these approaches with their physicians. The differences in the reported percentages may reflect differences in the definitions of complementary approaches used in the studies, as well as differences in the communication practices of different groups of patients.
Safety
- Delaying conventional cancer treatment can decrease the chances of remission or cure. Do not use unproven products or practices to postpone or replace conventional medical treatment for cancer.
- Some complementary health approaches may interfere with cancer treatments or be unsafe for cancer patients. For example, the herb St. John’s wort, which is sometimes used for depression, can make some cancer drugs less effective.
- Other complementary approaches may be harmful if used inappropriately. For example, to make massage therapy safe for people with cancer, it may be necessary to avoid massaging places on the body that are directly affected by the disease or its treatment (for example, areas where the skin is sensitive following radiation therapy).
- People who have been diagnosed with cancer should consult the health care providers who are treating them for cancer before using any complementary health approach for any purpose—whether or not it is cancer-related.
What the Science Says
No complementary health product or practice has been proven to cure cancer. Some complementary approaches may help people manage cancer symptoms or treatment side effects and improve their quality of life.
Incorporating Complementary Health Approaches Into Cancer Care
In 2009, the Society for Integrative Oncology issued evidence-based clinical practice guidelines for health care providers to consider when incorporating complementary health approaches in the care of cancer patients. The guidelines point out that, when used in addition to conventional therapies, some of these approaches help to control symptoms and enhance patients’ well-being. The guidelines warn, however, that unproven methods should not be used in place of conventional treatment because delayed treatment of cancer reduces the likelihood of a remission or cure.
A comprehensive summary of research on complementary health approaches for cancer is beyond the scope of this fact sheet. The following sections provide an overview of the research status of some commonly used complementary approaches, highlighting results from a few reviews and studies focusing on preventing and treating the disease, as well as managing cancer symptoms and treatment side effects.
Talking With Your Health Care Providers About Complementary Approaches and Cancer
The National Institutes of Health (NIH) has resources that can help you talk with your health care providers about complementary approaches and cancer.
- NCI’s Office of Cancer Complementary and Alternative Medicine has a workbook to help cancer patients and their health care providers talk about and keep track of complementary approaches that patients are using. You can download it here: cam.cancer.gov/talking_about_cam.html?cid=ARcam_camnews.
- NCCAM’s Time to Talk campaign has tips to help both patients and health care providers discuss complementary health approaches.
Complementary Health Approaches for Cancer Symptoms and Treatment Side Effects
Some complementary health approaches, such as acupuncture, massage therapy, mindfulness-based stress reduction, and yoga, may help people manage cancer symptoms or the side effects of treatment. However, some approaches may interfere with conventional cancer treatment or have other risks.People who have been diagnosed with cancer should consult their health care providers before using any complementary health approach.
- There is substantial evidence that acupuncture can help to manage treatment-related nausea and vomiting in cancer patients. There is not enough evidence to judge whether acupuncture is effective in relieving cancer pain or other symptoms such as treatment-related hot flashes. Complications from acupuncture are rare, as long as the acupuncturist uses sterile needles and proper procedures. Chemotherapy and radiation therapy weaken the body’s immune system, so it is especially important for acupuncturists to follow strict clean-needle procedures when treating cancer patients.
- Recent studies suggest that the herb ginger may help to control nausea related to cancer chemotherapy when used in addition to conventional anti-nausea medication.
- Studies suggest that massage therapy may help to relieve symptoms experienced by people with cancer, such as pain, nausea, anxiety, and depression. However, investigators have been unable to reach definite conclusions about the effects of massage therapy because of the limited amount of rigorous research in this field. People with cancer should consult their health care providers before having massage therapy to find out if any special precautions are needed. The massage therapist should not use deep or intense pressure without the health care providers’ approval and may need to avoid certain sites, such as areas directly over a tumor or those where the skin is sensitive following radiation therapy.
- There is evidence that mindfulness-based stress reduction, a type of meditation training, can help cancer patients relieve anxiety, stress, fatigue, and general mood and sleep disturbances, thus improving their quality of life. Most participants in mindfulness studies have been patients with early-stage cancer, primarily breast cancer, so the evidence favoring mindfulness training is strongest for this group of patients.
- Preliminary evidence indicates that yoga may help to improve anxiety, depression, distress, and stress in people with cancer. It also may help to lessen fatigue in breast cancer patients and survivors. However, only a small number of yoga studies in cancer patients have been completed, and some of the research has not been of the highest quality. Because yoga involves physical activities, it is important for people with cancer to talk with their health care providers in advance to find out whether any aspects of yoga might be unsafe for them.
- Various studies suggest possible benefits of hypnosis, relaxation therapies, and biofeedback to help patients manage cancer symptoms and treatment side effects.
- A 2008 review of the research literature on herbal supplements and cancer concluded that although several herbs have shown promise for managing side effects and symptoms such as nausea and vomiting, pain, fatigue, and insomnia, the scientific evidence is limited, and many clinical trials have not been well designed. Use of herbs for managing symptoms also raises concerns about potential negative interactions with conventional cancer treatments.
Coping With Cancer
People who have cancer, or who have been treated for cancer, may have physical or emotional difficulties as a result of the disease or its treatment. Many conventional approaches can help people cope with these problems. For example, counseling may help people who are distressed about being diagnosed with cancer, medicines can control nausea related to chemotherapy, and exercise may help decrease treatment-related fatigue. Some people find that complementary approaches also help them cope with cancer and improve their quality of life. In addition, using complementary approaches can help people feel they are playing an active part in their own care. If you have cancer or if you have been treated for cancer, be sure to tell your health care providers about all approaches—both conventional and complementary—that you are using. Your health care providers need this information so they can make sure that all aspects of your care work well together. Additional information on coping with cancer is available from NCI at www.cancer.gov/cancertopics/coping.
Complementary Health Approaches for Cancer Treatment
This section discusses complementary health approaches to directly treat cancer (that is, to try to cure the disease or cause a remission).
No complementary approach has been shown to cure cancer or cause it to go into remission. Some products or practices that have been advocated for cancer treatment may interfere with conventional cancer treatments or have other risks. People who have been diagnosed with cancer should consult their health care providers before using any complementary health approach.
- Studies on whether herbal supplements or substances derived from them might be of value in cancer treatment are in their early stages, and scientific evidence is limited. Herbal supplements may have side effects, and some may interact in harmful ways with drugs, including drugs used in cancer treatment.
- The effects of taking vitamin and mineral supplements, including antioxidant supplements,during cancer treatment are uncertain. NCI advises cancer patients to talk to their health care providers before taking any supplements.
- A 2010 NCCAM-supported trial of a standardized shark cartilage extract, taken in addition to chemotherapy and radiation therapy, showed no benefit in patients with advanced lung cancer. An earlier, smaller study in patients with advanced breast or colorectal cancers also showed no benefit from the addition of shark cartilage to conventional treatment.
- A 2011 systematic review of research on laetrile found no evidence that it is effective as a cancer treatment. Laetrile can be toxic, especially if taken orally, because it contains cyanide.
Beware of Cancer Treatment Frauds
The U.S. Food and Drug Administration (FDA) and the Federal Trade Commission (FTC) have warned the public to be aware of fraudulent cancer treatments. Cancer treatment frauds are not new, but in recent years it has become easier for the people who market them to reach the public using the Internet.
Some fraudulent cancer treatments are harmful by themselves, and others can be indirectly harmful because people may delay seeking medical care while they try them, or because the fraudulent product interferes with the effectiveness of proven cancer treatments.
The people who sell fraudulent cancer treatments often market them with claims such as “scientific breakthrough,” “miraculous cure,” “secret ingredient,” “ancient remedy,” “treats all forms of cancer,” or “shrinks malignant tumors.” The advertisements may include personal stories from people who have taken the product, but such stories—whether or not they’re real—aren’t reliable evidence that a product is effective. Also, a money-back guarantee is not proof that a product works.
If you’re considering using any anticancer product that you’ve seen in an advertisement, talk to your health care provider first. Additional information on cancer-related health frauds is available from the FDA and from the FTC.
Complementary Health Approaches for Cancer Prevention
A large 2012 clinical trial has shown that taking a multivitamin/mineral supplement may slightly reduce the risk of cancer in older men. No other complementary health approach has been shown to be helpful in preventing cancer, and some have been linked with increased health risks.
Vitamin and Mineral Supplements. The results of a study of older men completed in 2012 indicate that taking a multivitamin/mineral supplement slightly reduces the risk of cancer. In this study, which was part of the Physicians’ Health Study II (a complex trial that tested several types of supplements), more than 14,000 male U.S. physicians were randomly assigned to take a multivitamin/mineral supplement or a placebo (an identical-appearing product that did not contain vitamins and minerals) for 11 years. Those who took the supplement had 8 percent fewer total cancers than those who took the placebo.
Other studies of vitamins and minerals—most of which evaluated supplements containing only one or a few nutrients—have not found protective effects against cancer. Some of these studies identified possible risks of supplementing with high doses of certain vitamins or related substances. Examples of research results include the following:
- In another part of the Physicians’ Health Study II (not the part described above), supplementing with relatively high doses of either vitamin E or vitamin C did not reduce the risks of prostate cancer or total cancer in men aged 50 or older. Men taking vitamin E had an increased risk of hemorrhagic stroke (a type of stroke caused by bleeding in the brain).
- A 2010 meta-analysis of 22 clinical trials found no evidence that antioxidant supplements (vitamins A, C, and E; beta-carotene; and selenium) help to prevent cancer.
- Two large-scale studies found evidence that supplements containing beta-carotene increased the risk of lung cancer among smokers.
- The Selenium and Vitamin E Cancer Prevention Trial (SELECT), funded by NCI, NCCAM, and other agencies at NIH, showed that selenium and vitamin E supplements, taken either alone or together, did not prevent prostate cancer. It also showed that vitamin E supplements, taken alone, significantlyincreased the risk of prostate cancer in healthy men. There was no increase in prostate cancer risk when vitamin E and selenium were taken together. The doses of selenium and vitamin E used in this study were substantially higher than those typically included in multivitamin/mineral supplements.
- Although substantial evidence suggests that calcium may help protect against colorectal cancer, the evidence of potential benefit from calcium in supplement form is limited and inconsistent. Therefore, NCI does not recommend the use of calcium supplements to reduce the risk of colorectal cancer.
Other Natural Products. A 2009 systematic review of 51 studies with more than 1.6 million participants found “insufficient and conflicting” evidence regarding an association between consuming green tea and cancer prevention. Several other natural products, including Ginkgo biloba, isoflavones, noni, pomegranate, and grape seed extract, have been investigated for possible cancer-preventive effects, but the evidence on these substances is too limited for any conclusions to be reached.
Do You Want To Learn More About Cancer Prevention?
People can reduce their risk of cancer in many ways. They include avoiding exposure to agents that cause cancer (such as cigarette smoke), having tests (such as colonoscopies) that find precancerous conditions early, and, for some people who are at high risk, taking medicines to reduce cancer risk (chemoprevention). Additional information on cancer prevention is available from NCI.
NIH Research on Complementary Health Approaches for Cancer
Both NCI and NCCAM fund many laboratory studies and clinical trials related to cancer. Some ongoing studies are investigating:
- The effects of genetic factors and intakes of calcium and magnesium on the risk of developing precancerous colorectal polyps
- Mechanisms of action of natural products that may be of value in cancer prevention or treatment, such as bamboo extract, grape seed extract, white tea, red ginseng, and S-adenosyl-L-methionine (SAMe)
- The use of acupuncture for difficulty in swallowing after treatment for head and neck cancer
- Mind and body practices to improve sleep in cancer patients.
Additional information is available from NCI and from NCCAM.
If You Have Been Diagnosed With Cancer and Are Considering a Complementary Health Approach
- Cancer patients need to make informed decisions about using complementary health approaches. NCCAM and NCI have written a brochure that can help: Thinking About Complementary and Alternative Medicine: A Guide for People With Cancer.
- Gather information about the complementary health product or practice that interests you, and then discuss it with your health care providers. If you have been diagnosed with cancer, it is especially important to talk with your health care providers before you start using any new complementary health approach. If you are already using a complementary approach, tell your health care providers about it, even if your reason for using it has nothing to do with cancer. Some approaches may interfere with standard cancer treatment or may be harmful when used along with standard treatment. Examples of questions to ask include:
- What is known about the benefits and risks of this product or practice? Do the benefits outweigh the risks?
- What are the potential side effects?
- Will this approach interfere with conventional treatment?
- Can you refer me to a practitioner?
- Do not use any health product or practice that has not been proven safe and effective to replace conventional cancer care or as a reason to postpone seeing your health care provider about any health problem.
- Tell all your health care providers about any complementary health approaches you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care. For tips about talking with your health care providers about complementary health approaches, seeNCCAM’s Time to Talk campaign.
Key References
- Boehm K, Borrelli F, Ernst E, et al. Green tea (Camellia sinensis) for the prevention of cancer.Cochrane Database of Systematic Reviews. 2009;(3):CD005004. Accessed at http://www.thecochranelibrary.com on February 14, 2013.
- Cramer H, Lange S, Klose P, et al. Can yoga improve fatigue in breast cancer patients? A systematic review. Acta Oncologica. 2012;51(4):559–560.
- Deng GE, Frenkel M, Cohen L, et al. Evidence-based clinical practice guidelines for integrative oncology: complementary therapies and botanicals. Journal of the Society for Integrative Oncology. 2009;7(3):85–120.
- Elkins G, Fisher W, Johnson A. Mind-body therapies in integrative oncology. Current Treatment Options in Oncology. 2010;11(3–4):128–140.
- Ernst E. Massage therapy for cancer palliation and supportive care: a systematic review of randomised clinical trials. Supportive Care in Cancer. 2009;17(4):333–337.
- Ernst E, Lee MS. Acupuncture for palliative and supportive cancer care: a systematic review of systematic reviews. Journal of Pain and Symptom Management. 2010;40(1):e3–5.
- Gaziano JM, Glynn RJ, Christen WG, et al. Vitamins E and C in the prevention of prostate and total cancer in men: the Physicians’ Health Study II randomized controlled trial. JAMA. 2009;301(1):52–62.
- Gaziano JM, Sesso HD, Christen WG, et al. Multivitamins in the prevention of cancer in men: the Physicians’ Health Study II randomized controlled trial. JAMA. 2012;308(18):E1–E10.
- Klein EA, Thompson IM Jr, Tangen CM, et al. Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA. 2011;306(14):1549–1556.
- Ledesma D, Kumano H. Mindfulness-based stress reduction and cancer: a meta-analysis. Psycho-Oncology. 2009;18(6):571–579.
- Lin K-Y, Hu Y-T, Chang K-J, et al. Effects of yoga on psychological health, quality of life, and physical health of patients with cancer: a meta-analysis. Evidence-Based Complementary and Alternative Medicine. 2011;2011:659876.
- Lippman SM, Klein EA, Goodman PJ, et al. Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT).JAMA. 2009;301(1):39–51.
- Lu C, Lee JJ, Komaki R, et al. Chemoradiotherapy with or without AE-941 in stage III non-small cell lung cancer: a randomized phase III trial. Journal of the National Cancer Institute. 2010;102(12):859–865.
- Manksy PJ, Wallerstedt DB. Complementary medicine in palliative care and cancer symptom management. Cancer Journal. 2006;12(5):425–431.
- Mao JJ, Palmer CS, Healy KE, et al. Complementary and alternative medicine use among cancer survivors: a population-based study. Journal of Cancer Survivorship. 2011;5(1):8–17.
- Milazzo S, Ernst E, Lejeune S, et al. Laetrile treatment for cancer. Cochrane Database of Systematic Reviews. 2011;(11):CD005476. Accessed at http://www.thecochranelibrary.com on February 14, 2013.
- Miller S, Stagl J, Wallerstedt DB, et al. Botanicals used in complementary and alternative medicine treatment of cancer: clinical science and future perspectives. Expert Opinion on Investigational Drugs. 2008;17(9):1353–1364.
- Myung S-K, Kim Y, Ju W, et al. Effects of antioxidant supplements on cancer prevention: meta-analysis of randomized controlled trials. Annals of Oncology. 2010;21(1):166–179.
- Paley CA, Johnson MI, Tashani OA, et al. Acupuncture for cancer pain in adults. Cochrane Database of Systematic Reviews. 2011;(1):CD007753. Accessed at http://www.thecochranelibrary.com on February 14, 2013.
- Pillai AK, Sharma KK, Gupta YK, et al. Anti-emetic effect of ginger powder versus placebo as an add-on therapy in children and young adults receiving high emetogenic chemotherapy. Pediatric Blood & Cancer. 2011;56(2):234–238.
- Ryan JL, Heckler CE, Roscoe JA, et al. Ginger (Zingiber officinale) reduces acute chemotherapy-induced nausea: a URCC CCOP study of 576 patients. Supportive Care in Cancer. 2012;20(7):1479–1489.
- Wilkinson S, Barnes K, Storey L. Massage for symptom relief in patients with cancer: systematic review. Journal of Advanced Nursing. 2008;63(5):430–439.
For More Information
NCCAM Clearinghouse
The NCCAM Clearinghouse provides information on NCCAM and complementary health approaches, including publications and searches of Federal databases of scientific and medical literature. The Clearinghouse does not provide medical advice, treatment recommendations, or referrals to practitioners.
National Cancer Institute
The National Cancer Institute is the Federal Government’s lead agency for cancer research. The National Cancer Institute’s Office of Cancer Complementary and Alternative Medicine coordinates and enhances the National Cancer Institute’s activities in CAM research.
NCI’s Office of Cancer Complementary and Alternative Medicine
NCI’s Office of Cancer Complementary and Alternative Medicine coordinates and enhances NCI’s activities in complementary and alternative medicine research.
Information on complementary and alternative medicine in cancer treatment:www.cancer.gov/cancertopics/pdq/cam/cam-cancer-treatment/patient/page3/AllPages
PubMed®
A service of the National Library of Medicine (NLM), PubMed® contains publication information and (in most cases) brief summaries of articles from scientific and medical journals.
NIH Clinical Research Trials and You
The National Institutes of Health (NIH) has created a Web site, NIH Clinical Research Trials and You, to help people learn about clinical trials, why they matter, and how to participate. The site includes questions and answers about clinical trials, guidance on how to find clinical trials through ClinicalTrials.gov and other resources, and stories about the personal experiences of clinical trial participants. Clinical trials are necessary to find better ways to prevent, diagnose, and treat diseases.
Acknowledgments
NCCAM thanks Cornelia Ulrich, Ph.D., German Cancer Research Center; Susan Folkman, Ph.D., University of California, San Francisco; Jun James Mao, M.D., University of Pennsylvania; Elizabeth Austin, M.S., Robin Baldwin, B.S.N., Barbara McMakin, M.S., and Jeffrey White, M.D., National Cancer Institute; and Carol Pontzer, Ph.D., and John (Jack) Killen, Jr., M.D., NCCAM, for their contributions to the 2013 update of this publication.
This publication is not copyrighted and is in the public domain. Duplication is encouraged.
* Note: PDF files require a viewer such as the free Adobe Reader.
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Traditional Chinese Medicines – Some Are Dangerous
As I’ve stated in previous postings here, choose your alternative/traditional/complementary medicines and therapies wisely.
Also, include herbs, supplements and traditional medicines in “medications” lists you share with your healthcare provider, pharmacist, or any healthcare professional you are consulting. Many of these non-prescription items can interfere with any prescription medicine you are taking.
The Related Resources section below has links to trusted resources. However, they are not meant to replace advice from you health care provider.
From the 14 April 2012 article at Medical News Today
Australian border officials seized 15 TCMs (traditional Chinese medicines), which researchers from the Murdoch University analyzed to reveal the animal and plant composition by using new DNA sequencing technology. The results, published in PLoS Genetics, showed that some of the analyzed TCM samples contained potentially toxic plant ingredients, allergens, as well as traces of endangered animals.Leading researcher, Dr. Bunce, and a Murdoch University Australian Research Council Future Fellow commented:
“TCMs have a long cultural history, but today consumers need to be aware of the legal and health safety issues before adopting them as a treatment option.”
Related Resources
- Drugs, Supplements, and Herbal Information (from a MedlinePlus page)
Prescription and over-the-counter medication information contains answers to many general questions including topics as what a drug is used for, precautions, side effects, dietary instructions, and overdoses. From the American Society of Health System Pharmacists
- HerbMed®
an interactive, electronic herbal database – provides hyperlinked access to the scientific data underlying the use of herbs for health. It is an impartial, evidence-based information resource provided by the nonprofit Alternative Medicine Foundation, Inc. This public site provides access to 20 of the most popular herbs.- Herbs at a Glance (US National Center for Complementary and Alternative Medicine)
a series of fact sheets that provides basic information about specific herbs or botanicals—common names, uses, potential side effects, and resources for more information.- Herbal Links
a compilation of sites that the researchers at the University of Iowa Drug Information Service consider to be the highest quality and most useful to pharmacists for finding information concerning herbal medicines.
Longwood Herbal Task Force
This site has in-depth monographs about herbal products and supplements written by health professionals and students. It provides clinical information summaries, patient fact sheets, and information about toxicity and interactions as well as relevant links. The task force is a cooperative effort of the staff and students from Children’s Hospital, the Massachusetts College of Pharmacy and Health Sciences, and the Dana Farber Cancer Institute. Drug Information Portal (US National Library of Medicine)
Search by drug. Information includes some basic resources (as that at MedlinePlus) plus some more technical ones (as Toxilogical Data and Literature)- Dietary Supplements Labels Database Information about label ingredients in more than 6,000 selected brands of dietary supplements. It enables users to compare label ingredients in different brands. Information is also provided on the “structure/function” claims made by manufacturers.These claims by manufacturers have not been evaluated by the Food and Drug Administration. Companies may not market as dietary supplements any products that are intended to diagnose, treat, cure or prevent any disease.
- NCCAM Director’s Page – It’s Time to Talk (March 13, 2012)
- Time to Talk is a recently launched NCAAM series which encourages folks to discuss complementary health practices with their health care providersThe director notes the following
- We know that nearly 40 percent of Americans use some kind of complementary health practice. But we also know that most patients do not proactively disclose use of complementary health practices to their health care providers. Likewise, most providers don’t initiate the discussion with their patients. As a physician, I strongly believe that patients and their health care providers need to talk openly about all of their health care practices to ensure safe, coordinated care. Talking not only allows fully integrated care, but it also minimizes risks of interactions with a patient’s conventional treatments.
- This month’s Time to Talk includes these tips
- List the complementary health practices you use on your patient history form. When completing the patient history form, be sure to include everything you use—from acupuncture to zinc. It’s important to give health care providers a full picture of what you do to manage your health.
- At each visit, be sure to tell your providers about what complementary health approaches you are using. Don’t forget to include over-the-counter and prescription medicines, as well as dietary and herbal supplements. Make a list in advance, or download and print this wallet card and take it with you. Some complementary health approaches can have an effect on conventional medicine, so your provider needs to know.
- If you are considering a new complementary health practice, ask questions. Ask your health care providers about its safety, effectiveness, and possible interactions with medications (both prescription and nonprescription).
Related articles
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- Chinese herbal medicines contained toxic mix – CBC.ca (drugstoresource.wordpress.com)
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- Chinese medicines contain traces of endangered animals (telegraph.co.uk)
- Breaking down traditional Chinese medicine. (green.blogs.nytimes.com)
- Dangers of Chinese Medicine Brought to Light by DNA Studies (news.sciencemag.org)
- Dangers of Chinese Medicine Brought to Light by DNA Studies (news.sciencemag.org)
Headaches and Complementary Health Practices
Headaches are one of the most common forms of pain. More than 45 million Americans have headaches severe enough to require the help of a health care professional. Headaches occur when pain-sensitive nerve endings around the scalp, in the blood vessels that surround the skull, in the lining around the brain, and in other areas around the head send impulses to the part of the brain that interprets pain signals from the rest of the body. Some headaches are related to tender spots in head, neck, and shoulder muscles.
Researchers are studying treatments for different types of headaches, including a number of complementary health practices. This issue provides information on “what the science says” about the effectiveness and safety of selected complementary health practices for headaches, includingrelaxation training, biofeedback, acupuncture, tai chi, cognitive-behavioral therapy,massage, spinal manipulation, and dietary supplements.
Read more about what the science says
Jump to: Clinical Guidelines | Scientific Literature | Research Spotlights | Info for Patients
Age-old remedies using white tea, witch hazel and rose may be beneficial
Age-old remedies could hold the key to treating a wide range of serious medical problems, as well as keeping skin firmer and less wrinkled, according to scientists. Experts have discovered that white tea, witch hazel and the simple rose hold potential health and beauty properties which could be simply too good to ignore.
The research suggests a number of naturally-occurring substances may offer the hope of new treatments to block the progression of inflammation. It is credited with a major role in both the initiation and development of diseases ranging from cancer, diabetes and arthritis through to neuro-degenerative conditions and cardiovascular and pulmonary problems.
“For thousands of years people used natural remedies to try — and sometimes succeed — in curing their ailments and preserving their youth,” Professor Declan Naughton, from the University’s School of Life Sciences, said. “Now the latest research we have carried out suggests a number of naturally-occurring substances may offer the hope of new treatments to block the progression of inflammation.”….
….The new study builds on work undertaken by Professor Naughton and Kingston University PhD student Tamsyn Thring, along with the technical team from Neal’s Yard. They tested 21 plant extracts for evidence of their efficiency in fighting cancer and also in the battle against aging. Of the 21 extracts, three — white tea, witch hazel and rose — showed considerable potential, with white tea displaying the most marked results. “Indeed it appeared that drinking a simple cup of white tea might well help reduce an individual’s risk of cancer, rheumatoid arthritis or even just age-associated wrinkles,” Professor Naughton said.