[Interactive chart] Snake oil? Scientific evidence for popular nutritional supplements

 From the Web site

This image is a “balloon race”. The higher a bubble, the greater the evidence for its effectiveness. But the supplements are only effective for the conditions listed inside the bubble.

You might also see multiple bubbles for certain supps. These is because some supps affect a range of conditions, but the evidence quality varies from condition to condition. For example, there’s strong evidence that Green Tea is good for cholesterol levels. But evidence for its anti-cancer effects is conflicting. In these cases, we give a supp another bubble.

This visualisation generates itself from this Google Doc. So when new research comes out, we can quickly update the data and regenerate the image. (How cool is that??)

Sources: PubMed, Cochrane.org

 

The interactive chart allows one to filter by health condition and supplement type (as enzyme, plant/herb). Data in this Google spreadsheet.

 

Related resources

MEDLINE plus: Complementary and Alternative Medicine Trusted health information links from the US National Institutes of Health (NIH). Includes basic information, news, organizations, specific conditions, multimedia, financial issues, and more

Bandolier: Evidenced Based Thinking about Healthcare – Alternative Medicine
The site brings together the best evidence available about complementary and alternative therapies for consumers and professionals. It contains stories, systematic reviews and meta-analyses of complementary and alternative therapies with abstracts.

Herbs at a Glance  Series of brief fact sheets that provides basic information about specific herbs or botanicals—common names, what the science says, potential side effects and cautions, and resources for more information. NCCAM (National Center for Complementary and Alternative Medicine)

Office of Cancer Complementary Alternative Medicine  The NIH, National Cancer Institute (NCI) Office of Cancer Complementary and Alternative Medicine (OCCAM) was established in October 1998 to coordinate and enhance the activities of the National Cancer Institute (NCI) in the arena of complementary and alternative medicine (CAM)
Quackwatch.com  Nonprofit  whose purpose is to combat health-related frauds, myths, fads, and fallacies. Information on quackery, questionable therapies and more

 

Related articles

• Get to Know Your Library Resources: Massage Therapy
• FDA: Supplements, Meds Can Be Dangerous Mix
• Complementary Health Practices for U.S. Military, Veterans, and Families
• NCI sees role for feds in validating, processing wearables data
• Military Chronic Pain to Receive 5 Year, $22 Million Research Project
• Complementary and alternative medicine for veterans and military personnel — update from Medical Care
• What Is Reiki?

[Free ebook] Pain: Considering Complementary Approaches

 

From the National Center for Complementary and Alternative Medicine

Pain is the most common reason for seeking medical care. It is also a common reason why people turn to complementary health approaches.

We have collected our information on pain into an eBook you can download to your computer or mobile device.

If you have a Web-enabled device:

• Download the eBook as an ePub (for Nook, iPad, and more) (1MB EPUB)
• Download the eBook for Kindle (1.2MB MOBI)

 

Relaxation Techniques for Health: An Introduction | NCCAM

Relaxation Techniques for Health: An Introduction | NCCAM

Excerpts from the Web page at The  National Center for Complementary and Alternative Medicine

On this page:

• Key Points
• About Relaxation Techniques
• Use of Relaxation Techniques for Health in the United States
• How Relaxation Techniques May Work
• Status of Research on Relaxation Techniques
• NCCAM-Funded Research
• Side Effects and Risks
• Training, Licensing, and Certification
• If You Are Thinking About Using Relaxation Techniques for Health
• Key References
• For More Information

Introduction

Relaxation techniques include a number of practices such as progressive relaxation, guided imagery,biofeedback, self-hypnosis, and deep breathing exercises. The goal is similar in all: to consciously produce the body’s natural relaxation response, characterized by slower breathing, lower blood pressure, and a feeling of calm and well-being.

Relaxation techniques (also called relaxation response techniques) may be used by some to release tension and to counteract the ill effects of stress. Relaxation techniques are also used to induce sleep, reduce pain, and calm emotions. This fact sheet provides basic information about relaxation techniques, summarizes scientific research on effectiveness and safety, and suggests sources for additional information.

Key Points

• Relaxation techniques may be an effective part of an overall treatment plan for anxiety, depression, and some types of pain. Some research also suggests that these techniques may help with other conditions, such as ringing in the ears and overactive bladder. However, their ability to improve conditions such as high blood pressure and asthma is unclear.
• Relaxation techniques are generally safe.
• Do not use relaxation techniques to replace scientifically proven treatments or to postpone seeing a health care provider about a medical problem.
• Tell all your health care providers about any complementary health approaches you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care.

 

About Relaxation Techniques

Relaxation is more than a state of mind; it physically changes the way your body functions. When your body is relaxed breathing slows, blood pressure and oxygen consumption decrease, and some people report an increased sense of well-being. This is called the “relaxation response.” Being able to produce the relaxation response using relaxation techniques may counteract the effects of long-term stress, which may contribute to or worsen a range of health problems including depression, digestive disorders, headaches, high blood pressure, and insomnia.

Go here for the entire article

 

Related articles

• National Institute on Health article on Benefits of Yoga
• Massage Therapy for Health Purposes
• Breathing stimulates relaxation
• Acupuncture – An Introduction
• NCCAM- Herbs at a Glance
• The director of NCCAM wants a “nuanced conversation” about “complementary and alternative medicine”

 

Order or Download Your Free Patient Packet – Tips on How to Talk with your Health Care Provider

Order or Download Your Free Patient Packet | NCCAM

From the Web page

Order or Download Your Free Patient Packet

As part of the Time To Talk campaign, NCCAM has developed a packet of helpful materials to help you begin a dialogue with your health care providers. Order your packet online or call 1-888-644-6226 and use reference code D393.

Each packet contains:

• Backgrounder: The backgrounder provides information about the importance of health care providers and their patients talking about complementary health practices.Download PDF

 

• TELL tip sheet: This sheet provides tips for talking with health care providers.Download PDF

• Patient wallet card: This card will help to keep track of all medications, including dietary supplements and other complementary health products, and will be a handy reference during visits to your health care provider.Download PDF

• Get the Facts: Are You Considering Complementary and Alternative Medicine? This fact sheet will assist you in your decision making about using CAM.Download PDF

Order your packet online or call 1-888-644-6226 and use reference code D393.

 

Related Resources

• Patient involvement (including questions to ask your doctor) from US AHRQ (Association for Healthcare Research and Quality)
• Diagnosis and Treatment (including Quick Tips When Talking with your Doctor) from US AHRQ

Related articles

• Complementary Health Practices Information from NCAAM
• The director of NCCAM wants a “nuanced conversation” about “complementary and alternative medicine”
• National Institute on Health article on Benefits of Yoga
• About NCCAM
• NCCAM- Herbs at a Glance
• NCCAM features musical training lecture

Logo of the United States National Center for Complementary and Alternative Medicine , part of the National Institutes of Health. (Photo credit: Wikipedia)

 

 From the US National Center for Complementary and Alternative Medicine

 

Cancer and Complementary Health Approaches

Introduction

People with cancer want to do everything they can to combat the disease, manage its symptoms, and cope with the side effects of treatment. Many turn to complementary health approaches, including natural products, such as herbs (botanicals) and other dietary supplements, and mind and body practices, such as acupuncture, massage, and yoga.

This fact sheet was produced through a collaboration between the National Center for Complementary and Alternative Medicine (NCCAM) and the National Cancer Institute (NCI). It provides an introductory overview of complementary health approaches that have been studied for cancer prevention, treatment of the disease, or symptom management, including what the science says about their effectiveness and any concerns that have been raised about their safety.

 

Key Facts

• Symptom management. A substantial amount of scientific evidence suggests that some complementary health approaches may help to manage some symptoms of cancer and side effects of treatment. For other complementary approaches, the evidence is more limited.
• Disease treatment. At present, there is no convincing evidence that any complementary health approach is effective in curing cancer or causing it to go into remission.
• Cancer prevention. A 2012 study indicated that taking a multivitamin/mineral supplement may slightly reduce the risk of cancer in older men. No other complementary health approach has been shown to be helpful in preventing cancer.

 

Keep in Mind

• Unproven products or practices should not be used to replace or delay conventional medical treatment for cancer.
• Some complementary approaches can interfere with standard cancer treatments or have special risks for people who have been diagnosed with cancer. Before using any complementary health approach, people who have been diagnosed with cancer should talk with their health care providers to make sure that all aspects of their care work together.
• Tell all your health care providers about any complementary health approaches you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care.

 

About Cancer

Cancer is a term for diseases in which abnormal cells divide without control. Cancer cells can invade nearby tissues and spread to other parts of the body through the bloodstream and the lymph system. Although cancer is the second leading cause of death in the United States, improvements in screening, detection, treatment, and care have increased the number of cancer survivors, and experts expect the number of survivors to continue to increase in the coming years. Detailed information on cancer is available from NCI at www.cancer.gov.

 

About Complementary Health Approaches

Complementary health approaches are a group of diverse medical and health care systems, practices, and products whose origins come from outside of mainstream medicine. They include such products and practices as herbal supplements, other dietary supplements, meditation, spinal manipulation, and acupuncture.

The same careful scientific evaluation that is used to assess conventional therapies should be used to evaluate complementary approaches. Some complementary approaches are beginning to find a place in cancer treatment—not as cures, but as additions to treatment plans that may help patients cope with disease symptoms and side effects of treatment and improve their quality of life.

 

Use of Complementary Health Approaches for Cancer

Many people who have been diagnosed with cancer use complementary health approaches.

• According to the 2007 National Health Interview Survey (NHIS), which included a comprehensive survey on the use of complementary health approaches by Americans, 65 percent of respondents who had ever been diagnosed with cancer had used complementary approaches, as compared to 53 percent of other respondents. Those who had been diagnosed with cancer were more likely than others to have used complementary approaches for general wellness, immune enhancement, and pain management.
• Other surveys have also found that use of complementary health approaches is common among people who have been diagnosed with cancer, although estimates of use vary widely. Some data indicate that the likelihood of using complementary approaches varies with the type of cancer and with factors such as sex, age, and ethnicity. The results of surveys from 18 countries show that use of complementary approaches by people who had been diagnosed with cancer was more common in North America than in Australia/New Zealand or Europe and that use had increased since the 1970s and especially since 2000.
• Surveys have also shown that many people with cancer do not tell their health care providers about their use of complementary health approaches. In the NHIS, survey respondents who had been diagnosed with cancer told their health care providers about 15 percent of their herb use and 23 percent of their total use of complementary approaches. In other studies, between 32 and 69 percent of cancer patients and survivors who used dietary supplements or other complementary approaches reported that they discussed these approaches with their physicians. The differences in the reported percentages may reflect differences in the definitions of complementary approaches used in the studies, as well as differences in the communication practices of different groups of patients.

 

Safety

• Delaying conventional cancer treatment can decrease the chances of remission or cure. Do not use unproven products or practices to postpone or replace conventional medical treatment for cancer.
• Some complementary health approaches may interfere with cancer treatments or be unsafe for cancer patients. For example, the herb St. John’s wort, which is sometimes used for depression, can make some cancer drugs less effective.
• Other complementary approaches may be harmful if used inappropriately. For example, to make massage therapy safe for people with cancer, it may be necessary to avoid massaging places on the body that are directly affected by the disease or its treatment (for example, areas where the skin is sensitive following radiation therapy).
• People who have been diagnosed with cancer should consult the health care providers who are treating them for cancer before using any complementary health approach for any purpose—whether or not it is cancer-related.

 

What the Science Says

No complementary health product or practice has been proven to cure cancer. Some complementary approaches may help people manage cancer symptoms or treatment side effects and improve their quality of life.

Incorporating Complementary Health Approaches Into Cancer Care

In 2009, the Society for Integrative Oncology issued evidence-based clinical practice guidelines for health care providers to consider when incorporating complementary health approaches in the care of cancer patients. The guidelines point out that, when used in addition to conventional therapies, some of these approaches help to control symptoms and enhance patients’ well-being. The guidelines warn, however, that unproven methods should not be used in place of conventional treatment because delayed treatment of cancer reduces the likelihood of a remission or cure.

A comprehensive summary of research on complementary health approaches for cancer is beyond the scope of this fact sheet. The following sections provide an overview of the research status of some commonly used complementary approaches, highlighting results from a few reviews and studies focusing on preventing and treating the disease, as well as managing cancer symptoms and treatment side effects.

Talking With Your Health Care Providers About Complementary Approaches and Cancer

The National Institutes of Health (NIH) has resources that can help you talk with your health care providers about complementary approaches and cancer.

• NCI’s Office of Cancer Complementary and Alternative Medicine has a workbook to help cancer patients and their health care providers talk about and keep track of complementary approaches that patients are using. You can download it here: cam.cancer.gov/talking_about_cam.html?cid=ARcam_camnews.
• NCCAM’s Time to Talk campaign has tips to help both patients and health care providers discuss complementary health approaches.

Complementary Health Approaches for Cancer Symptoms and Treatment Side Effects

Some complementary health approaches, such as acupuncture, massage therapy, mindfulness-based stress reduction, and yoga, may help people manage cancer symptoms or the side effects of treatment. However, some approaches may interfere with conventional cancer treatment or have other risks.People who have been diagnosed with cancer should consult their health care providers before using any complementary health approach.

• There is substantial evidence that acupuncture can help to manage treatment-related nausea and vomiting in cancer patients. There is not enough evidence to judge whether acupuncture is effective in relieving cancer pain or other symptoms such as treatment-related hot flashes. Complications from acupuncture are rare, as long as the acupuncturist uses sterile needles and proper procedures. Chemotherapy and radiation therapy weaken the body’s immune system, so it is especially important for acupuncturists to follow strict clean-needle procedures when treating cancer patients.
• Recent studies suggest that the herb ginger may help to control nausea related to cancer chemotherapy when used in addition to conventional anti-nausea medication.
• Studies suggest that massage therapy may help to relieve symptoms experienced by people with cancer, such as pain, nausea, anxiety, and depression. However, investigators have been unable to reach definite conclusions about the effects of massage therapy because of the limited amount of rigorous research in this field. People with cancer should consult their health care providers before having massage therapy to find out if any special precautions are needed. The massage therapist should not use deep or intense pressure without the health care providers’ approval and may need to avoid certain sites, such as areas directly over a tumor or those where the skin is sensitive following radiation therapy.
• There is evidence that mindfulness-based stress reduction, a type of meditation training, can help cancer patients relieve anxiety, stress, fatigue, and general mood and sleep disturbances, thus improving their quality of life. Most participants in mindfulness studies have been patients with early-stage cancer, primarily breast cancer, so the evidence favoring mindfulness training is strongest for this group of patients.
• Preliminary evidence indicates that yoga may help to improve anxiety, depression, distress, and stress in people with cancer. It also may help to lessen fatigue in breast cancer patients and survivors. However, only a small number of yoga studies in cancer patients have been completed, and some of the research has not been of the highest quality. Because yoga involves physical activities, it is important for people with cancer to talk with their health care providers in advance to find out whether any aspects of yoga might be unsafe for them.
• Various studies suggest possible benefits of hypnosis, relaxation therapies, and biofeedback to help patients manage cancer symptoms and treatment side effects.
• A 2008 review of the research literature on herbal supplements and cancer concluded that although several herbs have shown promise for managing side effects and symptoms such as nausea and vomiting, pain, fatigue, and insomnia, the scientific evidence is limited, and many clinical trials have not been well designed. Use of herbs for managing symptoms also raises concerns about potential negative interactions with conventional cancer treatments.

Coping With Cancer

People who have cancer, or who have been treated for cancer, may have physical or emotional difficulties as a result of the disease or its treatment. Many conventional approaches can help people cope with these problems. For example, counseling may help people who are distressed about being diagnosed with cancer, medicines can control nausea related to chemotherapy, and exercise may help decrease treatment-related fatigue. Some people find that complementary approaches also help them cope with cancer and improve their quality of life. In addition, using complementary approaches can help people feel they are playing an active part in their own care. If you have cancer or if you have been treated for cancer, be sure to tell your health care providers about all approaches—both conventional and complementary—that you are using. Your health care providers need this information so they can make sure that all aspects of your care work well together. Additional information on coping with cancer is available from NCI at www.cancer.gov/cancertopics/coping.

Complementary Health Approaches for Cancer Treatment

This section discusses complementary health approaches to directly treat cancer (that is, to try to cure the disease or cause a remission).

No complementary approach has been shown to cure cancer or cause it to go into remission. Some products or practices that have been advocated for cancer treatment may interfere with conventional cancer treatments or have other risks. People who have been diagnosed with cancer should consult their health care providers before using any complementary health approach.

• Studies on whether herbal supplements or substances derived from them might be of value in cancer treatment are in their early stages, and scientific evidence is limited. Herbal supplements may have side effects, and some may interact in harmful ways with drugs, including drugs used in cancer treatment.
• The effects of taking vitamin and mineral supplements, including antioxidant supplements,during cancer treatment are uncertain. NCI advises cancer patients to talk to their health care providers before taking any supplements.
• A 2010 NCCAM-supported trial of a standardized shark cartilage extract, taken in addition to chemotherapy and radiation therapy, showed no benefit in patients with advanced lung cancer. An earlier, smaller study in patients with advanced breast or colorectal cancers also showed no benefit from the addition of shark cartilage to conventional treatment.
• A 2011 systematic review of research on laetrile found no evidence that it is effective as a cancer treatment. Laetrile can be toxic, especially if taken orally, because it contains cyanide.

Beware of Cancer Treatment Frauds

The U.S. Food and Drug Administration (FDA) and the Federal Trade Commission (FTC) have warned the public to be aware of fraudulent cancer treatments. Cancer treatment frauds are not new, but in recent years it has become easier for the people who market them to reach the public using the Internet.

Some fraudulent cancer treatments are harmful by themselves, and others can be indirectly harmful because people may delay seeking medical care while they try them, or because the fraudulent product interferes with the effectiveness of proven cancer treatments.

The people who sell fraudulent cancer treatments often market them with claims such as “scientific breakthrough,” “miraculous cure,” “secret ingredient,” “ancient remedy,” “treats all forms of cancer,” or “shrinks malignant tumors.” The advertisements may include personal stories from people who have taken the product, but such stories—whether or not they’re real—aren’t reliable evidence that a product is effective. Also, a money-back guarantee is not proof that a product works.

If you’re considering using any anticancer product that you’ve seen in an advertisement, talk to your health care provider first. Additional information on cancer-related health frauds is available from the FDA and from the FTC.

Complementary Health Approaches for Cancer Prevention

A large 2012 clinical trial has shown that taking a multivitamin/mineral supplement may slightly reduce the risk of cancer in older men. No other complementary health approach has been shown to be helpful in preventing cancer, and some have been linked with increased health risks.

Vitamin and Mineral Supplements. The results of a study of older men completed in 2012 indicate that taking a multivitamin/mineral supplement slightly reduces the risk of cancer. In this study, which was part of the Physicians’ Health Study II (a complex trial that tested several types of supplements), more than 14,000 male U.S. physicians were randomly assigned to take a multivitamin/mineral supplement or a placebo (an identical-appearing product that did not contain vitamins and minerals) for 11 years. Those who took the supplement had 8 percent fewer total cancers than those who took the placebo.

Other studies of vitamins and minerals—most of which evaluated supplements containing only one or a few nutrients—have not found protective effects against cancer. Some of these studies identified possible risks of supplementing with high doses of certain vitamins or related substances. Examples of research results include the following:

• In another part of the Physicians’ Health Study II (not the part described above), supplementing with relatively high doses of either vitamin E or vitamin C did not reduce the risks of prostate cancer or total cancer in men aged 50 or older. Men taking vitamin E had an increased risk of hemorrhagic stroke (a type of stroke caused by bleeding in the brain).
• A 2010 meta-analysis of 22 clinical trials found no evidence that antioxidant supplements (vitamins A, C, and E; beta-carotene; and selenium) help to prevent cancer.
• Two large-scale studies found evidence that supplements containing beta-carotene increased the risk of lung cancer among smokers.
• The Selenium and Vitamin E Cancer Prevention Trial (SELECT), funded by NCI, NCCAM, and other agencies at NIH, showed that selenium and vitamin E supplements, taken either alone or together, did not prevent prostate cancer. It also showed that vitamin E supplements, taken alone, significantlyincreased the risk of prostate cancer in healthy men. There was no increase in prostate cancer risk when vitamin E and selenium were taken together. The doses of selenium and vitamin E used in this study were substantially higher than those typically included in multivitamin/mineral supplements.
• Although substantial evidence suggests that calcium may help protect against colorectal cancer, the evidence of potential benefit from calcium in supplement form is limited and inconsistent. Therefore, NCI does not recommend the use of calcium supplements to reduce the risk of colorectal cancer.

Other Natural Products. A 2009 systematic review of 51 studies with more than 1.6 million participants found “insufficient and conflicting” evidence regarding an association between consuming green tea and cancer prevention. Several other natural products, including Ginkgo biloba, isoflavones, noni, pomegranate, and grape seed extract, have been investigated for possible cancer-preventive effects, but the evidence on these substances is too limited for any conclusions to be reached.

Do You Want To Learn More About Cancer Prevention?

People can reduce their risk of cancer in many ways. They include avoiding exposure to agents that cause cancer (such as cigarette smoke), having tests (such as colonoscopies) that find precancerous conditions early, and, for some people who are at high risk, taking medicines to reduce cancer risk (chemoprevention). Additional information on cancer prevention is available from NCI.

 

NIH Research on Complementary Health Approaches for Cancer

Both NCI and NCCAM fund many laboratory studies and clinical trials related to cancer. Some ongoing studies are investigating:

• The effects of genetic factors and intakes of calcium and magnesium on the risk of developing precancerous colorectal polyps
• Mechanisms of action of natural products that may be of value in cancer prevention or treatment, such as bamboo extract, grape seed extract, white tea, red ginseng, and S-adenosyl-L-methionine (SAMe)
• The use of acupuncture for difficulty in swallowing after treatment for head and neck cancer
• Mind and body practices to improve sleep in cancer patients.

Additional information is available from NCI and from NCCAM.

 

If You Have Been Diagnosed With Cancer and Are Considering a Complementary Health Approach

• Cancer patients need to make informed decisions about using complementary health approaches. NCCAM and NCI have written a brochure that can help: Thinking About Complementary and Alternative Medicine: A Guide for People With Cancer.
• Gather information about the complementary health product or practice that interests you, and then discuss it with your health care providers. If you have been diagnosed with cancer, it is especially important to talk with your health care providers before you start using any new complementary health approach. If you are already using a complementary approach, tell your health care providers about it, even if your reason for using it has nothing to do with cancer. Some approaches may interfere with standard cancer treatment or may be harmful when used along with standard treatment. Examples of questions to ask include:
  • What is known about the benefits and risks of this product or practice? Do the benefits outweigh the risks?
  • What are the potential side effects?
  • Will this approach interfere with conventional treatment?
  • Can you refer me to a practitioner?
• Do not use any health product or practice that has not been proven safe and effective to replace conventional cancer care or as a reason to postpone seeing your health care provider about any health problem.
• Tell all your health care providers about any complementary health approaches you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care. For tips about talking with your health care providers about complementary health approaches, seeNCCAM’s Time to Talk campaign.

 

Key References

• Boehm K, Borrelli F, Ernst E, et al. Green tea (Camellia sinensis) for the prevention of cancer.Cochrane Database of Systematic Reviews. 2009;(3):CD005004. Accessed at http://www.thecochranelibrary.com on February 14, 2013.
• Cramer H, Lange S, Klose P, et al. Can yoga improve fatigue in breast cancer patients? A systematic review. Acta Oncologica. 2012;51(4):559–560.
• Deng GE, Frenkel M, Cohen L, et al. Evidence-based clinical practice guidelines for integrative oncology: complementary therapies and botanicals. Journal of the Society for Integrative Oncology. 2009;7(3):85–120.
• Elkins G, Fisher W, Johnson A. Mind-body therapies in integrative oncology. Current Treatment Options in Oncology. 2010;11(3–4):128–140.
• Ernst E. Massage therapy for cancer palliation and supportive care: a systematic review of randomised clinical trials. Supportive Care in Cancer. 2009;17(4):333–337.
• Ernst E, Lee MS. Acupuncture for palliative and supportive cancer care: a systematic review of systematic reviews. Journal of Pain and Symptom Management. 2010;40(1):e3–5.
• Gaziano JM, Glynn RJ, Christen WG, et al. Vitamins E and C in the prevention of prostate and total cancer in men: the Physicians’ Health Study II randomized controlled trial. JAMA. 2009;301(1):52–62.
• Gaziano JM, Sesso HD, Christen WG, et al. Multivitamins in the prevention of cancer in men: the Physicians’ Health Study II randomized controlled trial. JAMA. 2012;308(18):E1–E10.
• Klein EA, Thompson IM Jr, Tangen CM, et al. Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA. 2011;306(14):1549–1556.
• Ledesma D, Kumano H. Mindfulness-based stress reduction and cancer: a meta-analysis. Psycho-Oncology. 2009;18(6):571–579.
• Lin K-Y, Hu Y-T, Chang K-J, et al. Effects of yoga on psychological health, quality of life, and physical health of patients with cancer: a meta-analysis. Evidence-Based Complementary and Alternative Medicine. 2011;2011:659876.
• Lippman SM, Klein EA, Goodman PJ, et al. Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT).JAMA. 2009;301(1):39–51.
• Lu C, Lee JJ, Komaki R, et al. Chemoradiotherapy with or without AE-941 in stage III non-small cell lung cancer: a randomized phase III trial. Journal of the National Cancer Institute. 2010;102(12):859–865.
• Manksy PJ, Wallerstedt DB. Complementary medicine in palliative care and cancer symptom management. Cancer Journal. 2006;12(5):425–431.
• Mao JJ, Palmer CS, Healy KE, et al. Complementary and alternative medicine use among cancer survivors: a population-based study. Journal of Cancer Survivorship. 2011;5(1):8–17.
• Milazzo S, Ernst E, Lejeune S, et al. Laetrile treatment for cancer. Cochrane Database of Systematic Reviews. 2011;(11):CD005476. Accessed at http://www.thecochranelibrary.com on February 14, 2013.
• Miller S, Stagl J, Wallerstedt DB, et al. Botanicals used in complementary and alternative medicine treatment of cancer: clinical science and future perspectives. Expert Opinion on Investigational Drugs. 2008;17(9):1353–1364.
• Myung S-K, Kim Y, Ju W, et al. Effects of antioxidant supplements on cancer prevention: meta-analysis of randomized controlled trials. Annals of Oncology. 2010;21(1):166–179.
• Paley CA, Johnson MI, Tashani OA, et al. Acupuncture for cancer pain in adults. Cochrane Database of Systematic Reviews. 2011;(1):CD007753. Accessed at http://www.thecochranelibrary.com on February 14, 2013.
• Pillai AK, Sharma KK, Gupta YK, et al. Anti-emetic effect of ginger powder versus placebo as an add-on therapy in children and young adults receiving high emetogenic chemotherapy. Pediatric Blood & Cancer. 2011;56(2):234–238.
• Ryan JL, Heckler CE, Roscoe JA, et al. Ginger (Zingiber officinale) reduces acute chemotherapy-induced nausea: a URCC CCOP study of 576 patients. Supportive Care in Cancer. 2012;20(7):1479–1489.
• Wilkinson S, Barnes K, Storey L. Massage for symptom relief in patients with cancer: systematic review. Journal of Advanced Nursing. 2008;63(5):430–439.

 

For More Information

NCCAM Clearinghouse

The NCCAM Clearinghouse provides information on NCCAM and complementary health approaches, including publications and searches of Federal databases of scientific and medical literature. The Clearinghouse does not provide medical advice, treatment recommendations, or referrals to practitioners.

Toll-free in the U.S.:

1-888-644-6226

TTY (for deaf and hard-of-hearing callers):

1-866-464-3615

Web site:

nccam.nih.gov

E-mail:

info@nccam.nih.gov

National Cancer Institute

The National Cancer Institute is the Federal Government’s lead agency for cancer research. The National Cancer Institute’s Office of Cancer Complementary and Alternative Medicine coordinates and enhances the National Cancer Institute’s activities in CAM research.

Toll-free in the U.S.:

1-800-4-CANCER (1-800-422-6237)

Web site:

www.cancer.gov/cam

E-mail:

cancergovstaff@mail.nih.gov

NCI’s Office of Cancer Complementary and Alternative Medicine

NCI’s Office of Cancer Complementary and Alternative Medicine coordinates and enhances NCI’s activities in complementary and alternative medicine research.

Information on complementary and alternative medicine in cancer treatment:www.cancer.gov/cancertopics/pdq/cam/cam-cancer-treatment/patient/page3/AllPages

Web site:

cam.cancer.gov

PubMed®

A service of the National Library of Medicine (NLM), PubMed® contains publication information and (in most cases) brief summaries of articles from scientific and medical journals.

Web site:

www.ncbi.nlm.nih.gov/pubmed

NIH Clinical Research Trials and You

The National Institutes of Health (NIH) has created a Web site, NIH Clinical Research Trials and You, to help people learn about clinical trials, why they matter, and how to participate. The site includes questions and answers about clinical trials, guidance on how to find clinical trials through ClinicalTrials.gov and other resources, and stories about the personal experiences of clinical trial participants. Clinical trials are necessary to find better ways to prevent, diagnose, and treat diseases.

Web site:

www.nih.gov/health/clinicaltrials/

Acknowledgments

NCCAM thanks Cornelia Ulrich, Ph.D., German Cancer Research Center; Susan Folkman, Ph.D., University of California, San Francisco; Jun James Mao, M.D., University of Pennsylvania; Elizabeth Austin, M.S., Robin Baldwin, B.S.N., Barbara McMakin, M.S., and Jeffrey White, M.D., National Cancer Institute; and Carol Pontzer, Ph.D., and John (Jack) Killen, Jr., M.D., NCCAM, for their contributions to the 2013 update of this publication.

This publication is not copyrighted and is in the public domain. Duplication is encouraged.

NCCAM has provided this material for your information. It is not intended to substitute for the medical expertise and advice of your primary health care provider. We encourage you to discuss any decisions about treatment or care with your health care provider. The mention of any product, service, or therapy is not an endorsement by NCCAM.

* Note: PDF files require a viewer such as the free Adobe Reader.

NCCAM Pub No.:

D453

Date Created:

September 2005

Last Updated:

May 2013

 

 

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More than Good Vibes: Researchers Propose the Science Behind Mindfulness

Mindfulness (Photo credit: Cathdew)

 

From the 29 October 2012  Brigham and Women’s Hospital press release

 

BOSTON, MA—Achieving mindfulness through meditation has helped people maintain a healthy mind by quelling negative emotions and thoughts, such as desire, anger and anxiety, and encouraging more positive dispositions such as compassion, empathy and forgiveness. Those who have reaped the benefits of mindfulness know that it works. But how exactly does it work?

Researchers at Brigham and Women’s Hospital (BWH) have proposed a new model that shifts how we think about mindfulness.  Rather than describing mindfulness as a single dimension of cognition, the researchers demonstrate that mindfulness actually involves a broad framework of complex mechanisms in the brain.

In essence, they have laid out the science behind mindfulness.

This new model of mindfulness is published in the October 25, 2012 issue of Frontiers in Human Neuroscience. The model was recently presented to His Holiness The Dalai Lama in a private meeting, entitled “Mind and Life XXIV: Latest Findings in Contemplative Neuroscience.”

The researchers identified several cognitive functions that are active in the brain during mindfulness practice. These cognitive functions help a person develop self-awareness, self-regulation, and self-transcendence (S-ART) which make up the transformative framework for the mindfulness process.

The S-ART framework explains the underlying neurobiological mechanisms by which mindfulness can facilitate self-awareness; reduce biases and negative thoughts; enhance the ability to regulate one’s behavior; and increase positive, pro-social relationships with oneself and others-all-in-all creating a sustainable healthy mind.

The researchers highlight six neuropsychological processes that are active mechanisms in the brain during mindfulness and which support S-ART. These processes include 1) intention and motivation, 2) attention regulation, 3) emotion regulation, 4) extinction and reconsolidation, 5) pro-social behavior, and 6) non-attachment and de-centering.

In other words, these processes begin with an intention and motivation to want to attain mindfulness, followed by an awareness of one’s bad habits. Once these are set, a person can begin taming him or herself to be less emotionally reactive and to recover faster from upsetting emotions.

“Through continued practice, the person can develop a psychological distance from any negative thoughts and can inhibit natural impulses that constantly fuel bad habits,” said David Vago, PhD, BWH Functional Neuroimaging Laboratory, Department of Psychiatry, and lead study author.

Vago also states that continued practice can also increase empathy and eliminate our attachments to things we like and aversions to things we don’t like.

“The result of practice is a new You with a new multidimensional skill set for reducing biases in one’s internal and external experience and sustaining a healthy mind,” said Vago.

The S-ART framework and neurobiological model proposed by the researchers differs from current popular descriptions of mindfulness as a way of paying attention, in the present moment, non-judgmentally. With the help of functional MRI, Vago and his team are currently testing the model in humans.

This research was supported by the Mind and Life Institute, Impact Foundation, and the National Center for Complementary and Alternative Medicine at the National Institutes of Health (5-R21AT002209-02).

 

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Scientific Results of Yoga for Health and Well-Being

 

Helen yoga (Photo credit: Wikipedia)

 

From the Web page at the US National Center for Complementary and Alternative Medicine

 

This video features the current scientific evidence for yoga as a complementary health practice, particularly for symptoms like chronic low-back pain. Viewers will also learn about research that explores the safety of yoga and how certain yoga poses can specifically affect a person’s body. The video also provides valuable “dos and don’ts” for consumers who are thinking about practicing yoga. This is the second installment in NCCAM’s The Science of Mind and Body Therapies video series.

Yoga is a mind and body practice with historical origins in ancient Indian philosophy. Like other meditative movement practices used for health purposes, various styles of yoga typically combine physical postures, breathing techniques, and meditation or relaxation.

 

 

On a related note…

 

Twitter Chat: Yoga

 

The experts for this month’s chat will be Dr. Karen Sherman, senior scientific investigator at Group Health Research Institute, and NCCAM staff member and certified yoga teacher Yasmine Kloth. The chat will take place on August 21, 2012 at 1:00 p.m. ET. Join at #nccamchat.
https://nccam.nih.gov/news/events/twitterchat?nav=upd

 

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Complementary Health Practices Information from NCAAM

NCAAM (National Center for Complementary and Alternative Medicine) recently published these pages/articlers

• Director’s Page – It’s Time to Talk (March 13, 2012)
  Time to Talk is a recently launched NCAAM series which encourages folks to discuss complementary health practices with their health care providers

  The director notes the following

  • We know that nearly 40 percent of Americans use some kind of complementary health practice. But we also know that most patients do not proactively disclose use of complementary health practices to their health care providers. Likewise, most providers don’t initiate the discussion with their patients. As a physician, I strongly believe that patients and their health care providers need to talk openly about all of their health care practices to ensure safe, coordinated care. Talking not only allows fully integrated care, but it also minimizes risks of interactions with a patient’s conventional treatments.

 

• This month’s Time to Talk includes these tips

1. List the complementary health practices you use on your patient history form. When completing the patient history form, be sure to include everything you use—from acupuncture to zinc.  It’s important to give health care providers a full picture of what you do to manage your health.
2. At each visit, be sure to tell your providers about what complementary health approaches you are using. Don’t forget to include over-the-counter and prescription medicines, as well as dietary and herbal supplements. Make a list in advance, or download and print this wallet card and take it with you. Some complementary health approaches can have an effect on conventional medicine, so your provider needs to know.
3. If you are considering a new complementary health practice, ask questions. Ask your health care providers about its safety, effectiveness, and possible interactions with medications (both prescription and nonprescription).

Don’t wait for your providers to ask about any complementary health practice you are using. Be proactive. Start the conversation.

• NCCAM TiwtterChate – Join us for monthly Twitter Chats that cover a variety of health topics and complementary approaches. Each month, a different topic will be selected. An expert in scientific and health issues will be available to answer your questions. Most chats will occur on the last Thursday of each month at 1 p.m. ET. Dates, times, and topics may change, and will be announced on this page and through Twitter and Facebook.

  Find us on Twitter: @NCCAM. To participate, use the hashtag: #nccamchat.

  Upcoming Chats

  March 30, 2012 Time to Talk

  Time to Talk Campaign—an educational campaign to encourage patients and their health care providers to openly discuss the use of complementary health practices.

  April 26, 2012 Asthma and Complementary Approaches

  May 31, 2012 Yoga

 

 

 

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Headaches and Complementary Health Practices

From the November 2011 Clinical Digest item of NCAAM (US National Center for  Complementary and Alternative Medicine)

Headaches are one of the most common forms of pain. More than 45 million Americans have headaches severe enough to require the help of a health care professional. Headaches occur when pain-sensitive nerve endings around the scalp, in the blood vessels that surround the skull, in the lining around the brain, and in other areas around the head send impulses to the part of the brain that interprets pain signals from the rest of the body. Some headaches are related to tender spots in head, neck, and shoulder muscles.

Researchers are studying treatments for different types of headaches, including a number of complementary health practices. This issue provides information on “what the science says” about the effectiveness and safety of selected complementary health practices for headaches, includingrelaxation training, biofeedback, acupuncture, tai chi, cognitive-behavioral therapy,massage, spinal manipulation, and dietary supplements.

Read more about what the science says

Jump to: Clinical Guidelines | Scientific Literature | Research Spotlights | Info for Patients

 

In the News: Dietary Supplements Research [NCCAM News and Events]

In the News: Dietary Supplements Research (from the US National Center for Complementary and Alternative Medicine)

via In the News: Dietary Supplements Research [NCCAM News and Events].

 

Three recently published studies have highlighted the use and research surrounding natural products.

• Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT) in the Journal of the American Medical Association.
• Effect of increasing doses of saw palmetto extract on lower urinary tract symptoms: a randomized trial in the Journal of the American Medical Association.
• Monounsaturated, trans, and saturated fatty acids and cognitive decline in women in the Journal of the American Geriatrics Society.

Many people take natural products in an effort to be well and stay healthy. In fact, according to the 2007 NHIS survey, 17.7 percent of American adults had used “natural products” (i.e., dietary supplements other than vitamins and minerals) in the past 12 months. It is important to study the safety and efficacy of widely used natural products that hold promise for treating or preventing disease or symptom management so that consumers, health care providers, and policy makers can make informed health care decisions.

NCCAM Research Spotlights

• Vitamin E Supplements Increase Incidence of Prostate Cancer, According to SELECT study (October 2011)
• Saw Palmetto Extract No More Effective Than Placebo for Urinary Symptoms in Men (September 2011)
• Study Explores Relationship Between Fatty Acids and Cognitive Decline in Women(May 2011)

Other Resources

• Dietary and Herbal Supplements
• Dietary Supplements and Mortality Rate in Older Women (NCI)

Related resources

• Drugs, Herbs, Vitamins, and Supplements (links to reputable resources)

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