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General interest items edited by Janice Flahiff

EPA Improves Access to Information on Hundreds of Chemicals

 


From the 15 June 2011 EPA Press Release

Searchable databases on chemical toxicity and exposure data now available

WASHINGTON – The U.S. Environmental Protection Agency (EPA) is making it easier to find data about chemicals. EPA is releasing two databases – the Toxicity Forecaster database (ToxCastDB) and a database of chemical exposure studies (ExpoCastDB) – that scientists and the public can use to access chemical toxicity and exposure data. Improved access supports EPA Administrator Lisa P. Jackson’s priorities of protecting Americans’ health by assuring the safety of chemicals and expanding the conversation on environmentalism.

“Chemical safety is a major priority of EPA and its research,” said Dr. Paul Anastas, assistant administrator of EPA’s Office of Research and Development. “These databases provide the public access to chemical information, data and results that we can use to make better-informed and timelier decisions about chemicals to better protect people’s health.”

ToxCastDB users can search and download data from over 500 rapid chemical tests conducted on more than 300 environmental chemicals. ToxCast uses advanced scientific tools to predict the potential toxicity of chemicals and to provide a cost-effective approach to prioritizing which chemicals of the thousands in use require further testing. ToxCast is currently screening 700 additional chemicals, and the data will be available in 2012.

ExpoCastDB consolidates human exposure data from studies that have collected chemical measurements from homes and child care centers. Data include the amounts of chemicals found in food, drinking water, air, dust, indoor surfaces and urine. ExpoCastDB users can obtain summary statistics of exposure data and download datasets. EPA will continue to add internal and external chemical exposure data and advanced user interface features to ExpoCastDB.

The new databases link together two important pieces of chemical research – exposure and toxicity data – both of which are required when considering potential risks posed by chemicals. The databases are connected through EPA’s Aggregated Computational Toxicology Resource (ACToR), an online data warehouse that collects data on over 500,000 chemicals from over 500 public sources.

Users can now access 30 years worth of animal chemical toxicity studies that were previously only found in paper documents, data from rapid chemical testing, and various chemical exposure measurements through one online resource. The ability to link and compare these different types of data better informs EPA’s decisions about chemical safety.

More information about the databases:
ToxCastDB: http://actor.epa.gov/actor/faces/ToxCastDB/Home.jsp
ExpoCastDB: http://actor.epa.gov/actor/faces/ExpoCastDB/Home.jsp
ACToR: http://actor.epa.gov 

June 23, 2011 Posted by | Consumer Health, Finding Aids/Directories, Librarian Resources | , , , , , , | Leave a comment

EPA Opens Access to Database on Chemical Hazard, Exposure and Toxicity Data


The U.S. Environmental Protection Agency (EPA) is making it easier to find chemical information online. EPA is releasing a database, called ToxRefDB, which allows scientists and the interested public to search and download thousands of toxicity testing results on hundreds of chemicals. ToxRefDB captures 30 years and $2 billion of testing results.

“Tens of thousands of chemicals are in commerce and current chemical testing is expensive and time consuming. Results from chemical testing are scattered throughout different sources,” said Dr. Robert Kavlock, director of EPA’s National Center for Computational Toxicology. “ToxRefDB allows the public to search, find and compare available studies about chemical toxicity and potential health effects.” 

ToxRefDB (Toxicity Reference Database) captures thousands of in vivo animal toxicity studies on hundreds of chemicals. The database:

  • Stores detailed study design, dosing, and observed treatment-related effects using standardized vocabulary.
  • Provides detailed chemical toxicity data, for the first time, in a publically accessible and searchable format.
  • Enables linkages to other public hazard, exposure and risk resources by integrating with ACToR (Aggregated Computational Toxicology Resource).
  • Captures over 30 years and $2 billion of animal testing results.
  • Connects to another EPA chemical screening tool called ToxCast, a multi-year, multi-million dollar effort that uses advanced science tools to help efficiently (~$20K per chemical) understand biological processes impacted by chemicals that may lead to adverse health effects.

From: EPA Opens Access to Chemical Information/Searchable database on chemical hazard, exposure and toxicity data now available

May 5, 2010 Posted by | Uncategorized | , , | Leave a comment

   

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