There Is No Such Thing As A Safe Tan: GW Researchers Break Tanning Misconceptions

Blue Ultraviolet Light Lamp (Photo credit: epSos.de)

From the 24 July 2012 article at Medical News Today

A new study conducted by GW School of Medicine and Health Sciences (SMHS) researchers Edward C. De Fabo, Ph.D., Frances P. Noonan, Ph.D., and Anastas Popratiloff, M.D., Ph.D., has been published in the journal Nature Communications. Their paper, entitled “Melanoma induction by ultraviolet A but not ultraviolet B radiation requires melanin pigment,” was published in June 2012.

“This is the first time that UV-induced melanin formation (tanning), traditionally thought to protect against skin cancer, is shown to be directly involved in melanomaformation in mammals,” said De Fabo, who is professor emeritus at SMHS. “Skin melanoma is the most lethal of the skin cancers. Our study shows that we were able to discover this new role for melanin by cleanly separating UVA from UVB and exposing our experimental melanoma animal model with these separated wavebands using our unique UV light system designed and set up at GW. Dermatologists have been warning for years there is no such thing as a safe tan and this new data appears to confirm this.” ..

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“Also new is our discovery that UV induction of melanin, as a melanoma-causing agent, works when skin is exposed only to UVA and not UVB radiation. This is especially important since melanoma formation has been correlated with sunbed use as many epidemiological studies have shown. One possible reason for this is that tanning lamps are capable of emitting UVA radiation up to 12 times, or higher, the UVA intensity of sunlight at high noon. Melanin plus UVA is known to cause photo-oxidation, a suspected, but still to be proved, mechanism for the formation of melanoma as we describe in our study,” De Fabo said. 

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