Health and Medical News and Resources

General interest items edited by Janice Flahiff

6 Things Every Woman Should Know About Yeast Infections [Reblog]

From the 25 July 2015 Time blog by Jennifer So

The symptoms can mimic other problems

One study found that as few as 11% of women who have never had a yeast infection could identify the symptoms, while other research has found that only one-third of women who thought they had a yeast infection actually did. Why the confusion?

The signs are similar to other down-there problems. If you have a yeast infection, you might notice burning, itching, pain during sex, and a thick white odorless discharge.

But if it smells fishy, it may instead be bacterial vaginosis (BV), and if you have only burning and pain during urination, that suggests a urinary tract infection. Bottom line: It can be difficult to figure out.

First-timer? Go to the doctor if you think you have one

 

Read the entire post here

July 28, 2015 Posted by | Consumer Health, Health News Items | , , | Leave a comment

How cranberries impact infection-causing bacteria

From the 15 July 2013 article at EurkeAlert

How cranberries impact infection-causing bacteria

Research points to potential role for cranberry derivatives in implantable medical devices

 IMAGE: Professor Nathalie Tufenkji is in her McGill University lab.

Click here for more information. 

Consuming cranberry products has been anecdotally associated with prevention of urinary tract infections (UTIs) for over 100 years. But is this popular belief a myth, or scientific fact?

In recent years, some studies have suggested that cranberries prevent UTIs by hindering bacteria from sticking to the walls of the urinary tract, thanks to phytochemicals known as proanthocyanidins (PACs). Yet the mechanisms by which cranberry materials may alter bacterial behaviour have not been fully understood.

Now, researchers in McGill University’s Department of Chemical Engineering are shedding light on the biological mechanisms by which cranberries may impart protective properties against urinary tract and other infections. Two new studies, spearheaded by Prof. Nathalie Tufenkji, add to evidence of cranberries’ effects on UTI-causing bacteria. The findings also point to the potential for cranberry derivatives to be used to prevent bacterial colonization in medical devices such as catheters.

In research results published online last month in the Canadian Journal of Microbiology, Prof. Tufenkji and members of her laboratory report that cranberry powder can inhibit the ability of Proteus mirabilis, a bacterium frequently implicated in complicated UTIs, to swarm on agar plates and swim within the agar. The experiments also show that increasing concentrations of cranberry powder reduce the bacteria’s production of urease, an enzyme that contributes to the virulence of infections.

These results build on previous work by the McGill lab, showing that cranberry materials hinder movement of other bacteria involved in UTIs. A genome-wide analysis of an uropathogenic E. colirevealed that expression of the gene that encodes for the bacteria’s flagellar filament was decreased in the presence of cranberry PACs.

The team’s findings are significant because bacterial movement is a key mechanism for the spread of infection, as infectious bacteria literally swim to disseminate in the urinary tract and to escape the host immune response.

“While the effects of cranberry in living organisms remain subject to further study, our findings highlight the role that cranberry consumption might play in the prevention of chronic infections,” Tufenkji says. “More than 150 million cases of UTI are reported globally each year, and antibiotic treatment remains the standard approach for managing these infections. The current rise of bacterial resistance to antibiotics underscores the importance of developing another approach.”

Another recent study led by Tufenkji in collaboration with McGill professor Showan Nazhat, a biomaterials expert at the Department of Mining and Materials Engineering, finds that cranberry-enriched silicone substrates impaired the spread of Proteus mirabilis. Those results, published online in the journal Colloids and Surfaces B: Biointerfaces, point to potential use for cranberry derivatives to hinder the spread of germs in implantable medical devices such as catheters, which are frequently implicated in UTIs.

“Based on the demonstrated bioactivity of cranberry, its use in catheters and other medical devices could someday yield considerable benefits to patient health,” Tufenkji says.

 

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Funding for the new studies was provided by the Natural Sciences and Engineering Research Council of Canada, the Canada Research Chairs program, the Wisconsin Cranberry Board, the Cranberry Institute, the Fonds québécois de la recherche sur la nature et les technologies, and the Fonds de la recherche en santé du Québec.

Link to the Canadian Journal of Microbiology article: http://www.nrcresearchpress.com/doi/abs/10.1139/cjm-2012-0744#.UctRHjvqlLc

Link to the Colloids and Surfaces B: Biointerfaces article: http://www.sciencedirect.com/science/article/pii/S0927776513002348

 

 

July 19, 2013 Posted by | Medical and Health Research News | , , , , , , , | Leave a comment

   

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