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General interest items edited by Janice Flahiff

[Repost] Here comes the sun to lower your blood pressure

Here comes the sun to lower your blood pressure.

From the 14 January 2014 ScienceDaily article

Exposing skin to sunlight may help to reduce blood pressure and thus cut the risk of heart attack and stroke, a study published in theJournal of Investigative Dermatology suggests.

Research carried out at the Universities of Southampton and Edinburgh shows that sunlight alters levels of the small messenger molecule, nitric oxide (NO) in the skin and blood, reducing blood pressure.

Martin Feelisch, Professor of Experimental Medicine and Integrative Biology at the University of Southampton, comments: “NO along with its breakdown products, known to be abundant in skin, is involved in the regulation of blood pressure. When exposed to sunlight, small amounts of NO are transferred from the skin to the circulation, lowering blood vessel tone; as blood pressure drops, so does the risk of heart attack and stroke.”

English: blood pressure measurement Deutsch: :...

English: blood pressure measurement Deutsch: :deBlutdruckmessung (Photo credit: Wikipedia)

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January 21, 2014 Posted by | Medical and Health Research News | , , | Leave a comment

Vitamin D Fraud: Lack of Truth in Labeling

Vitamin Packaging

Vitamin Packaging (Photo credit: colindunn)

 

From the 14 March post at Mind the Science Gap

 

….All told, the vitamin D content of “off-the-shelf” and compounded vitamins was highly variable

 

                            “ . . . potency ranged from 9% to 146%.”…

 

…. Why aren’t dietary supplements regulated like drugs or food additives?

 

….

 

 

 

 

 

 

March 22, 2013 Posted by | Nutrition | , , | Leave a comment

Low Vitamin D Levels Linked to Longevity, Surprising Study Shows

The correlation between vitamin D levels and longevity seems to be at least partially genetic.
Lowering levels of Vitamin D (as staying away from tanning beds) in itself does not necessarily lead to longer lives.
However, the authors believe further study is needed.

From the 5 November 2012 article at Science Daily

 Low levels of vitamin D may be associated with longevity, according to a study involving middle-aged children of people in their 90s published in CMAJ(Canadian Medical Association Journal).

We found that familial longevity was associated with lower levels of vitamin D and a lower frequency of allelic variation in the CYP2R1 gene, which was associated with higher levels of vitamin D,” writes Dr. Diana van Heemst, Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands, with coauthors.

Previous studies have shown that low levels of vitamin D are associated with increased rates of death, heart disease, diabetes, cancer, allergies, mental illness and other afflictions. However, it is not known whether low levels are the cause of these diseases or if they are a consequence…

Full text of the article is at http://www.cmaj.ca/content/early/2012/11/05/cmaj.120233.full.pdf+html

Abstract

Background: Low levels of 25(OH) vitamin D are associated with various age-related diseases and mortality, but causality has not been determined. We investigated vitamin D levels in the offspring of nonagenarians who had at least one nonagenarian sibling; these offspring have a lower prevalence of age-related diseases and a higher propensity to reach old age compared with their partners.

Methods: We assessed anthropometric characteristics, 25(OH) vitamin D levels, parathyroid hormone levels, dietary vitamin D intake and single nucleotide polymorphisms (SNPs) associated with vitamin D levels. We included offspring (n = 1038) of nonagenarians who had at least one nonagenarian sibling, and the offsprings’ partners (n = 461; controls) from the Leiden Longevity Study. We included age, sex, body mass index, month during which blood sampling was performed, dietary and supplemental vitamin D intake, and creatinine levels as possible confounding factors.

Results: The offspring had significantly lower levels of vitamin D (64.3 nmol/L) compared with controls (68.4 nmol/L; p = 0.002), independent of possible confounding factors. There was no difference in the levels of parathyroid hormone between groups. Compared with controls, the offspring had a lower frequency of a genetic variant in theCYP2R1 gene (rs2060793) (p = 0.04). The difference in vitamin D levels between offspring and controls persisted over the 2 most prevalent genotypes of this SNP.

Interpretation: Compared with controls, the offspring of nonagenarians who had at least one nonagenarian sibling had a reduced frequency of a common variant in theCYP2R1 gene, which predisposes people to high vitamin D levels; they also had lower levels of vitamin D that persisted over the 2 most prevalent genotypes. These results cast doubt on the causal nature of previously reported associations between low levels of vitamin D and age-related diseases and mortality.

 

 

Background: Low lev

 

November 8, 2012 Posted by | Nutrition | , , , | Leave a comment

   

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